Reddy A Vikram Simha, Reddy K Rajeev Kumar, Prakash A Ravi, Vidhyadhari Pavani
Reader, Department of Oral and Maxillofacial Pathology, G.Pulla Reddy Dental College. GPR Nagar , Nandyal Road, Kurnool, Andhra Pradesh, India .
Professor, Department of Prosthodontics, G.Pulla Reddy Dental College. GPR Nagar , Nandyal Road, Kurnool, Andhra Pradesh, India .
J Clin Diagn Res. 2014 Oct;8(10):ZD01-2. doi: 10.7860/JCDR/2014/8909.4952. Epub 2014 Oct 20.
The fibro osseous lesions of the jaws represent a diverse group of entities that are characterized by replacement of normal bone by a fibrous connective tissue matrix, with in which varying amounts of osteoid, immature and mature bone and in some instances, cementum like material are deposited. Fibro osseous lesions of the jaws include developmental (hamartomatous) lesions, reactive or dysplastic processes and neoplasms. Juvenile ossifying fibroma (JOF) is a unique fibro osseous neoplasm. It has 2 histopathological variants (1) Trabecular juvenile ossifying fibroma (TrJOF) and (2) Psammomatoid juvenile ossifying fibroma (PsJOF) with TrJOF affecting the jaws of children. Only 20% of the patients are over 15 years of age. JOF is more common in maxilla than mandible. Origin in extragnathic locations is extremely rare. It presents as an asymptomatic progressive, rapid expansion of jaws. Radiographically, tumour is well circumscribed, along with lack of continuity with adjacent bone, cortical expansion & perforation. Histopathologically it consists of a cell rich fibrous stroma with bundles of cellular osteoid and bone trabeculae without osteoblastic rimming, and aggregates of giant cells. It has a recurrence rate of 30-58%. Long standing lesions shows cystic changes. Aneurysmal bone cyst is the most common complication. Here we present a case report of 16 yr old female patient with clinical, radiographic & histopathological features of Trabecular JOF with Aneurysmal bone cyst.
颌骨的纤维骨性病变是一组多样的病变,其特征是正常骨被纤维结缔组织基质替代,其中有不同数量的类骨质、未成熟和成熟骨,在某些情况下还有牙骨质样物质沉积。颌骨的纤维骨性病变包括发育性(错构瘤性)病变、反应性或发育异常过程以及肿瘤。青少年骨化性纤维瘤(JOF)是一种独特的纤维骨性肿瘤。它有两种组织病理学变体:(1)小梁状青少年骨化性纤维瘤(TrJOF)和(2)砂粒样青少年骨化性纤维瘤(PsJOF),TrJOF影响儿童颌骨。只有20%的患者年龄超过15岁。JOF在上颌比下颌更常见。起源于颌骨外部位极为罕见。它表现为颌骨无症状的进行性快速膨胀。影像学上,肿瘤边界清晰,与相邻骨无连续性,皮质膨胀和穿孔。组织病理学上,它由富含细胞的纤维基质组成,有细胞性类骨质束和骨小梁,无成骨细胞包绕,还有巨细胞聚集。其复发率为30 - 58%。长期病变显示囊性改变。动脉瘤样骨囊肿是最常见的并发症。在此我们报告一例16岁女性患者,具有小梁状JOF伴动脉瘤样骨囊肿的临床、影像学和组织病理学特征。