Berg Nora G, Nolan Michael W, Paskova Tania, Ivanisevic Albena
Department of Materials Science and Engineering, and ‡Department of Electrical and Computer Engineering, North Carolina State University , Raleigh, North Carolina 27695, United States.
Langmuir. 2014 Dec 30;30(51):15477-85. doi: 10.1021/la5040245. Epub 2014 Dec 17.
An aqueous surface modification of gallium nitride was employed to attach biomolecules to the surface. The modification was a simple two-step process using a single linker molecule and mild temperatures. The presence of the peptide on the surface was confirmed with X-ray photoelectron spectroscopy. Subsequently, the samples were placed in water baths and exposed to ionizing radiation to examine the effects of the radiation on the material in an environment similar to the body. Surface analysis confirmed degradation of the surface of GaN after radiation exposure in water; however, the peptide molecules successfully remained on the surface following exposure to ionizing radiation. We hypothesize that during radiation exposure of the samples, the radiolysis of water produces peroxide and other reactive species on the sample surface. Peroxide exposure promotes the formation of a more stable layer of gallium oxyhydroxide which passivates the surface better than other oxide species.
采用氮化镓的水性表面改性方法将生物分子附着于其表面。该改性是一个使用单一连接分子且在温和温度下进行的简单两步过程。通过X射线光电子能谱确认了表面肽的存在。随后，将样品置于水浴中并暴露于电离辐射下，以在类似于人体的环境中研究辐射对该材料的影响。表面分析证实，在水中暴露于辐射后，氮化镓表面发生了降解；然而，肽分子在暴露于电离辐射后成功地保留在了表面。我们推测，在样品暴露于辐射期间，水的辐射分解会在样品表面产生过氧化物和其他活性物质。过氧化物的暴露促进了更稳定的羟基氧化镓层的形成，该层比其他氧化物种类能更好地使表面钝化。
