Deng Pei, Wu Le-Hao, Ren Yu-Ping, Wu Yi-Ping
Department of Plastic and Reconstructive Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
J Huazhong Univ Sci Technolog Med Sci. 2014 Dec;34(6):917-920. doi: 10.1007/s11596-014-1374-1. Epub 2014 Dec 6.
Conventional pedicled-flap based surgeries in treating breast cancer have their limitations. New surgical regimens are yet to be explored, which will follow the oncological principle of being "total tumor free", whilst fit into the unique characteristics of China's own medical system as well as patients' demand. From 2007 to 2013, 143 patients with early stage breast cancer were included in the study, with the average age of 46.1 years. Fifty-three patients were subjected to modified breast conserving surgery (MBCS)+latissimus dorsi (LD) flap reconstruction, 41 to skin sparing mastectomy (SSM)+implant+LD flap reconstruction, 29 to MBCS+distal transverse rectus abdominis myocutaneous (DTRAM) flap reconstruction, and 20 to SSM+DTRAM flap reconstruction. The results showed that out of the 143 patients, there was no graft loss. Minor complications included 4 cases of fat liquefaction, and 6 cases of seratoma, which all resolved after conservative treatment. Five patients had visible protuberance in the abdomen, but not leading to any gastrointestinal symptoms. The reconstructed breasts all presented good shape. 96.7% of the patients were satisfied with the outcome. The follow-up period varied from 6 months to 60 months, and only one patient died from tumor metastasis in the brain. No local recurrence occurred. It was concluded that these two modified pedicled-flap surgeries are readily practical, and aesthetically satisfactory, with high applicability in China. They do not compromise the oncological outcomes, but also are well-accepted by Chinese patients.
传统的基于带蒂皮瓣的乳腺癌手术存在局限性。新的手术方案仍有待探索,既要遵循“无瘤全切”的肿瘤学原则,又要适应中国自身医疗体系的独特特点以及患者需求。2007年至2013年,该研究纳入了143例早期乳腺癌患者,平均年龄46.1岁。53例患者接受了改良保乳手术(MBCS)+背阔肌(LD)皮瓣重建,41例接受了保留皮肤的乳房切除术(SSM)+植入物+LD皮瓣重建,29例接受了MBCS+远端腹直肌肌皮瓣(DTRAM)重建,20例接受了SSM+DTRAM皮瓣重建。结果显示,143例患者中无移植失败情况。轻微并发症包括4例脂肪液化和6例血清肿,经保守治疗后均痊愈。5例患者腹部有可见隆起,但未导致任何胃肠道症状。重建乳房外形均良好。96.7%的患者对手术效果满意。随访时间为6个月至60个月,仅1例患者死于脑肿瘤转移。无局部复发。结论是,这两种改良带蒂皮瓣手术操作简便,美观效果令人满意,在中国适用性高。它们不影响肿瘤学治疗效果,也为中国患者所接受。