Dinh T V, Slavin R E, Bhagavan B S, Hannigan E V, Tiamson E M, Yandell R B
Department of Obstetrics and Gynecology, University of Texas, Galveston.
Obstet Gynecol. 1989 Sep;74(3 Pt 1):388-92.
Forty-seven cases of mixed müllerian tumors of the uterus were analyzed clinically and pathologically. All patients but one were postmenopausal. Vaginal bleeding was the most frequent presenting symptom, followed by abdominal mass and pelvic pain. Long-term survival was found only in those cases in which the tumor was localized to the uterus (surgical stage I), particularly if it arose from a benign endometrial polyp. No correlation could be established between survival and tumor size, depth of myometrial invasion, or histologic type of sarcoma. Tumors arising after previous irradiation had a poor prognosis. Treatment included surgery, radiation, and chemotherapy. The cumulative probability of 5-year survival was 35%.
对47例子宫混合性苗勒管肿瘤进行了临床和病理分析。除1例患者外，所有患者均为绝经后女性。阴道出血是最常见的首发症状，其次是腹部肿块和盆腔疼痛。仅在肿瘤局限于子宫（手术分期I期）的病例中发现长期生存，特别是当肿瘤起源于良性子宫内膜息肉时。生存与肿瘤大小、肌层浸润深度或肉瘤组织学类型之间未发现相关性。既往接受过放疗后发生的肿瘤预后较差。治疗包括手术、放疗和化疗。5年生存率的累积概率为35%。
