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西高止山脉獐牙菜属植物的植物化学成分、抗氧化活性及高效液相色谱图谱

Phytochemical composition, antioxidant activity and HPLC profiles of Swertia species from Western Ghats.

作者信息

Kshirsagar Parthraj, Chavan Jaykumar, Nimbalkar Mansingraj, Yadav Shrirang, Dixit Ghansham, Gaikwad Nikhil

机构信息

a Laboratory of Cytogenetics and Plant Breeding, Department of Botany , Shivaji University , Kolhapur 416004 , India.

出版信息

Nat Prod Res. 2015;29(8):780-4. doi: 10.1080/14786419.2014.986124. Epub 2014 Dec 6.

DOI:10.1080/14786419.2014.986124
PMID:25482162
Abstract

Swertia chirayita is one of the potential medicinal plants of the family Gentianaceae in traditional medicine. Due to its high demand and scarcity, trade of chirayita is affected by adulterants. Swertia species from Western Ghats were compared with S. chirayita for phytochemical characterisation and antioxidant activities by using different extracts. This study revealed that acetone is the best extraction solvent of phenolic and flavonoid compounds with antioxidant properties as compared with other extracts. S. chirayita showed better antioxidant activity than other species with highest content of phenolics and flavonoids. Among the species from Western Ghats, Swertia minor has better antioxidant properties with higher content of phenolics and flavonoids when compared with S. chirayita. Gallic acid was detected in all species under study by using HPLC analysis. The Swertia species under study showed similar phytochemical properties and antioxidant potential and hence their use as substitute to S. chirayita needs to be further investigated.

摘要

印度獐牙菜是传统医学中龙胆科具有潜在药用价值的植物之一。由于其需求量大且稀缺,印度獐牙菜的贸易受到掺假行为的影响。通过使用不同提取物,对西高止山脉的獐牙菜属植物与印度獐牙菜进行了植物化学特征和抗氧化活性的比较。这项研究表明,与其他提取物相比,丙酮是具有抗氧化特性的酚类和黄酮类化合物的最佳提取溶剂。印度獐牙菜表现出比其他物种更好的抗氧化活性,其酚类和黄酮类化合物含量最高。在西高止山脉的物种中,小花獐牙菜与印度獐牙菜相比,具有更好的抗氧化性能,酚类和黄酮类化合物含量更高。通过高效液相色谱分析在所有研究的物种中均检测到没食子酸。所研究的獐牙菜属植物表现出相似的植物化学性质和抗氧化潜力,因此它们作为印度獐牙菜替代品的用途需要进一步研究。

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