Galzin A M, Davous P, Roudier M, Lamour Y, Poirier M F, Langer S Z
Laboratoires d'Etudes et de Recherches Synthélabo (L.E.R.S.), Paris, France.
Psychiatry Res. 1989 Jun;28(3):289-94. doi: 10.1016/0165-1781(89)90209-6.
Platelet [3H]-imipramine binding was studied in patients with Alzheimer's disease and control subjects matched to the patients for age and sex. There were no differences in the binding parameters of [3H]-imipramine on platelet membranes from patients with Alzheimer's disease, when compared with the control group. These results suggest that [3H]-imipramine binding could be a useful tool to discriminate between demented and depressive patients in elderly populations.
