Ranjan Richa, Singh Lavleen, Arava Sudheer K, Singh Manoj Kumar
Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Indian J Dermatol. 2014 Nov;59(6):567-70. doi: 10.4103/0019-5154.143514.
Skin biopsies are usually undertaken to confirm a clinical diagnosis, to remove a lesion, and to determine the adequacy of excised tissue margin. A surgical margin is technically defined as the "edge" of the tissue removed. The term is especially pertinent when the tissue excised is suspected of being involved by a malignant process. One of the most important predictive and prognostic factors of a malignant lesion is whether the margins of the resected specimen are involved by the tumor or not. The purpose of this review is to provide an insight into grossing of a skin biopsy specimen with emphasis on techniques and reporting of excision biopsy margins.
皮肤活检通常用于确认临床诊断、切除病变组织以及确定切除组织边缘是否足够。手术切缘在技术上被定义为切除组织的“边缘”。当切除的组织疑似有恶性病变时，这个术语尤为重要。恶性病变最重要的预测和预后因素之一是切除标本的边缘是否被肿瘤累及。本综述的目的是深入探讨皮肤活检标本的取材，重点是切除活检边缘的技术和报告。
