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本文引用的文献

1
Primary orbital liposarcoma.原发性眼眶脂肪肉瘤
J Craniofac Surg. 2011 May;22(3):1139-41. doi: 10.1097/SCS.0b013e3182108fdd.
2
MDM2-positive atypical lipomatous neoplasm/well-differentiated liposarcoma versus spindle cell lipoma of the orbit.MDM2 阳性非典型脂肪肉瘤/高级别分化脂肪肉瘤与眼窝部梭形细胞脂肪瘤的鉴别诊断。
Ophthalmic Plast Reconstr Surg. 2010 Nov-Dec;26(6):413-5. doi: 10.1097/IOP.0b013e3181cd62eb.
3
Primary orbital liposarcoma.原发性眼眶脂肪肉瘤。
Ophthalmology. 2010 Mar;117(3):606-14. doi: 10.1016/j.ophtha.2009.08.017. Epub 2009 Dec 22.
4
MDM2 and CDK4 immunostainings are useful adjuncts in diagnosing well-differentiated and dedifferentiated liposarcoma subtypes: a comparative analysis of 559 soft tissue neoplasms with genetic data.MDM2和CDK4免疫染色在诊断高分化和去分化脂肪肉瘤亚型中是有用的辅助手段:对559例软组织肿瘤与基因数据的比较分析
Am J Surg Pathol. 2005 Oct;29(10):1340-7. doi: 10.1097/01.pas.0000170343.09562.39.
5
Primary liposarcoma of the orbit: a clinicopathologic study of seven cases.眼眶原发性脂肪肉瘤:7例临床病理研究
Ann Diagn Pathol. 2001 Oct;5(5):255-66. doi: 10.1053/adpa.2001.27911.
6
Liposarcoma: new entities and evolving concepts.脂肪肉瘤:新实体与不断演变的概念
Ann Diagn Pathol. 2000 Aug;4(4):252-66. doi: 10.1053/adpa.2000.8133.
7
Orbital liposarcoma.眼眶脂肪肉瘤
Otolaryngol Head Neck Surg. 1994 Jul;111(1):111-5. doi: 10.1177/019459989411100119.
8
Primary liposarcoma of the orbit. Problems in the diagnosis and management of five cases.眼眶原发性脂肪肉瘤:5例诊断与处理中的问题
Ophthalmology. 1989 Feb;96(2):180-91. doi: 10.1016/s0161-6420(89)32916-2.

伪装成血管瘤的眼眶脂肪肉瘤。

Orbital liposarcoma masquerading as a hemangioma.

作者信息

Vrcek Ivan, Hogan Robert N, Gilliland Grant

机构信息

Department of Ophthalmology (Vrcek, Hogan) and the Department of Pathology (Hogan), The University of Texas Southwestern Medical Center, Dallas, Texas; and Texas Ophthalmic Plastic, Reconstructive, and Orbital Surgery Associates, Dallas, Texas (Gilliland).

出版信息

Proc (Bayl Univ Med Cent). 2014 Oct;27(4):359-60. doi: 10.1080/08998280.2014.11929159.

DOI:10.1080/08998280.2014.11929159
PMID:25484512
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4255867/
Abstract

Liposarcomas are the most common soft tissue sarcomas in adulthood, comprising approximately 20% of all sarcomas; most present in the extremities and retroperitoneum (1). Despite the large amount of adipose tissue in the orbit, orbital liposarcomas are rare. Diagnosis can be challenging due to the rarity of the entity and the pathological similarity to benign adipose tumors (2, 3). Fortunately, the advent of immunohistochemical staining has aided in diagnosis. Management of orbital liposarcoma also can be challenging, as illustrated by the case described herein (4).

摘要

脂肪肉瘤是成人最常见的软组织肉瘤,约占所有肉瘤的20%;大多数发生于四肢和腹膜后(1)。尽管眼眶内有大量脂肪组织,但眼眶脂肪肉瘤却很罕见。由于该实体罕见且在病理上与良性脂肪肿瘤相似,诊断颇具挑战性(2, 3)。幸运的是,免疫组织化学染色技术的出现有助于诊断。如下文所述病例所示,眼眶脂肪肉瘤的治疗也可能具有挑战性(4)。