Vrcek Ivan, Hogan Robert N, Gilliland Grant
Department of Ophthalmology (Vrcek, Hogan) and the Department of Pathology (Hogan), The University of Texas Southwestern Medical Center, Dallas, Texas; and Texas Ophthalmic Plastic, Reconstructive, and Orbital Surgery Associates, Dallas, Texas (Gilliland).
Proc (Bayl Univ Med Cent). 2014 Oct;27(4):359-60. doi: 10.1080/08998280.2014.11929159.
Liposarcomas are the most common soft tissue sarcomas in adulthood, comprising approximately 20% of all sarcomas; most present in the extremities and retroperitoneum (1). Despite the large amount of adipose tissue in the orbit, orbital liposarcomas are rare. Diagnosis can be challenging due to the rarity of the entity and the pathological similarity to benign adipose tumors (2, 3). Fortunately, the advent of immunohistochemical staining has aided in diagnosis. Management of orbital liposarcoma also can be challenging, as illustrated by the case described herein (4).
脂肪肉瘤是成人最常见的软组织肉瘤,约占所有肉瘤的20%;大多数发生于四肢和腹膜后(1)。尽管眼眶内有大量脂肪组织,但眼眶脂肪肉瘤却很罕见。由于该实体罕见且在病理上与良性脂肪肿瘤相似,诊断颇具挑战性(2, 3)。幸运的是,免疫组织化学染色技术的出现有助于诊断。如下文所述病例所示,眼眶脂肪肉瘤的治疗也可能具有挑战性(4)。