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4-氯-N-{[1-(4-氯苯甲酰基)哌啶-4-基]甲基}苯甲酰胺一水合物的晶体结构

Crystal structure of 4-chloro-N-{[1-(4-chloro-benzo-yl)piperidin-4-yl]meth-yl}benzamide monohydrate.

作者信息

Prathebha K, Reuben Jonathan D, Sathya S, Jovita J, Usha G

机构信息

PG and Research Department of Physics, Queen Mary's College, Chennai-4, Tamilnadu, India.

Department of Chemistry, Madras Christian College, Chennai-59, India.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2014 Sep 3;70(Pt 10):o1080. doi: 10.1107/S1600536814018522. eCollection 2014 Oct 1.

DOI:10.1107/S1600536814018522
PMID:25484682
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4257193/
Abstract

In the title compound, C20H20Cl2N2O2·H2O, the piperidine ring adopts a chair conformation with the two substituent benzene rings inclined to one another [dihedral angle 84.63 (9)°]. In the crystal, the components are linked by Ow-H⋯O, N-H⋯Ow (w = water) and C-H⋯O hydrogen bonds, generating a sheet structure lying parallel to (101).

摘要

在标题化合物C₂₀H₂₀Cl₂N₂O₂·H₂O中，哌啶环呈椅式构象，两个取代苯环相互倾斜[二面角84.63 (9)°]。在晶体中，各组分通过Ow-H⋯O、N-H⋯Ow（w = 水）和C-H⋯O氢键相连，形成平行于(101)的层状结构。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cea1/4257193/c26f7ddff37a/e-70-o1080-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cea1/4257193/ffab44fc5b63/e-70-o1080-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cea1/4257193/00ed1511f29c/e-70-o1080-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cea1/4257193/c26f7ddff37a/e-70-o1080-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cea1/4257193/ffab44fc5b63/e-70-o1080-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cea1/4257193/00ed1511f29c/e-70-o1080-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cea1/4257193/c26f7ddff37a/e-70-o1080-fig3.jpg

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