非支持性养育方式影响非裔美国人青年期的端粒长度：通过物质使用进行中介作用。
Nonsupportive parenting affects telomere length in young adulthood among African Americans: mediation through substance use.
作者信息
Beach Steven R H, Lei Man Kit, Brody Gene H, Yu Tianyi, Philibert Robert A
机构信息
Center for Family Research.
Department of Psychiatry, University of Iowa.
出版信息
J Fam Psychol. 2014 Dec;28(6):967-72. doi: 10.1037/fam0000039.
Abstract
Telomere length (TL) is an indicator of age-related changes at the cellular level associated with heightened mortality risk. The effect of nonsupportive parenting (NSP) during late adolescence and young adulthood on TL 5 years later was examined in a sample of N = 183 young adult African Americans to determine if effects of NSP on TL were mediated by substance use. Results indicated that the effect of caregiver reported NSP on diminished TL was mediated by escalation of drinking and smoking in young adulthood, even after controlling effects of socioeconomic status risk, gender, BMI, young adult stress, and intervention status. Results suggest that prevention of NSP may influence later physical health consequences by influencing substance use trajectory.
摘要
端粒长度（TL）是细胞水平上与死亡风险增加相关的年龄相关变化的一个指标。在183名年轻成年非裔美国人的样本中，研究了青春期后期和成年早期非支持性养育（NSP）对5年后TL的影响，以确定NSP对TL的影响是否由物质使用介导。结果表明，即使在控制了社会经济地位风险、性别、体重指数、年轻成人压力和干预状态的影响后，照顾者报告的NSP对TL缩短的影响仍由成年期饮酒和吸烟的增加介导。结果表明，预防NSP可能通过影响物质使用轨迹来影响后期的身体健康后果。
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