Institute of Toxicology and Genetics (ITG), Karlsruhe Institute of Technology , 76021 Karlsruhe, Germany.
Nano Lett. 2015 Jan 14;15(1):675-81. doi: 10.1021/nl5041836. Epub 2014 Dec 18.
Reactive superhydrophobic surfaces are highly promising for biotechnological, analytical, sensor, or diagnostic applications but are difficult to realize due to their chemical inertness. In this communication, we report on a photoactive, inscribable, nonwettable, and transparent surface (PAINTS), prepared by polycondensation of trichlorovinylsilane to form thin transparent reactive porous nanofilament on a solid substrate. The PAINTS shows superhydrophobicity and can be conveniently functionalized with the photoclick thiol-ene reaction. In addition, we show for the first time that the PAINTS bearing vinyl groups can be easily modified with disulfides under UV irradiation. The effect of superhydrophobicity of PAINTS on the formation of high-resolution surface patterns has been investigated. The developed reactive superhydrophobic coating can find applications for surface biofunctionalization using abundant thiol or disulfide bearing biomolecules, such as peptides, proteins, or antibodies.
反应性超疏水表面在生物技术、分析、传感器或诊断应用方面具有广阔的前景，但由于其化学惰性，很难实现。在本通讯中，我们报告了一种光活性、可刻蚀、不可润湿和透明的表面（PAINTS），它是通过三氯乙烯基硅烷的缩聚反应在固体基底上形成薄的透明反应性多孔纳米纤维而制备的。PAINTS 表现出超疏水性，并可以方便地通过光点击硫醇-烯反应进行功能化。此外，我们首次表明，带有乙烯基的 PAINTS 在紫外光照射下可以很容易地用二硫化物进行修饰。我们研究了 PAINTS 的超疏水性对形成高分辨率表面图案的影响。所开发的反应性超疏水涂层可用于表面生物功能化，使用丰富的含巯基或二硫键的生物分子，如肽、蛋白质或抗体。
