Barnes S C, Shepherd D E T, Espino D M, Bryan R T
School of Mechanical Engineering, University of Birmingham, Birmingham B15 2TT, UK.
School of Mechanical Engineering, University of Birmingham, Birmingham B15 2TT, UK.
J Mech Behav Biomed Mater. 2015 Feb;42:168-76. doi: 10.1016/j.jmbbm.2014.11.017. Epub 2014 Nov 25.
The aim of this study was to measure the viscoelastic properties of bladder tissue. Porcine bladders were dissected into rectangular strips and loops. Dynamic Mechanical Analysis was used to measure the viscoelastic properties of the bladder tissue (storage and loss stiffness) tested in a frequency range of up to 10 Hz. Storage stiffness was found to be consistently higher than loss stiffness. Average storage stiffness was found to be 1.89 N/mm and 0.74 N/mm for looped and rectangular samples, respectively. Average loss stiffness was found to be 0.24 N/mm and 0.11 N/mm for looped and rectangular samples, respectively. The results of this study are important for computational modelling of the bladder and for ensuring that engineered bladder tissues have physiological viscoelastic properties.
本研究的目的是测量膀胱组织的粘弹性特性。将猪膀胱切成矩形条带和环状。采用动态力学分析来测量在高达10Hz频率范围内测试的膀胱组织的粘弹性特性(储能刚度和损耗刚度)。发现储能刚度始终高于损耗刚度。对于环状和矩形样本,平均储能刚度分别为1.89N/mm和0.74N/mm。对于环状和矩形样本,平均损耗刚度分别为0.24N/mm和0.11N/mm。本研究结果对于膀胱的计算建模以及确保工程化膀胱组织具有生理粘弹性特性具有重要意义。