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原发性脑非霍奇金淋巴瘤患者经类固醇治疗后完全缓解

Steroid-induced complete remission in a case of primary cerebral non-Hodgkin's lymphoma.

作者信息

Pohl P, Oberhuber G, Dietze O, Vogl G, Pallua A K, Plangger C A, Huber H

机构信息

Department of Neurology, University of Innsbruck, Austria.

出版信息

Clin Neurol Neurosurg. 1989;91(3):247-50. doi: 10.1016/0303-8467(89)90119-4.

DOI:10.1016/0303-8467(89)90119-4
PMID:2548790
Abstract

A case of a primary non-Hodgkin's lymphoma of the CNS is reported in which a complete and stable disappearance of an enhancing mass lesion on the CT scan after treatment with dexamethasone was followed by the occurrence of a high-grade malignant lymphoma in the opposite hemisphere 18 months later. The long-lasting and stable remission suggests a direct oncolytic effect of corticosteroids on lymphoma cells. Furthermore, this case illustrates the usefulness of repeated CT examinations in patients with CNS lymphoma and steroid treatment.

摘要

报告了一例中枢神经系统原发性非霍奇金淋巴瘤病例,该病例在用地塞米松治疗后,CT扫描上强化肿块病变完全且稳定消失,18个月后在对侧半球出现了高级别恶性淋巴瘤。长期持续的稳定缓解提示皮质类固醇对淋巴瘤细胞有直接溶瘤作用。此外,该病例说明了重复CT检查在中枢神经系统淋巴瘤患者和类固醇治疗中的有用性。

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