Numakura Kazuyuki, Satoh Shigeru, Tsuchiya Norihiko, Saito Mitsuru, Nara Taketoshi, Huang Mingguo, Tsuruta Hiroshi, Akihama Susumu, Inoue Takamitsu, Narita Shintaro, Habuchi Tomonori
Akita University Graduate School of Medicine, Japan.
Prog Transplant. 2014 Dec;24(4):328-31. doi: 10.7182/pit2014372.
The development of primary malignant tumors is a distressing complication of organ transplant. However, the emergence of de novo renal cell carcinoma from a kidney allograft is rare. A 60-year-old man underwent living kidney transplant from a spousal donor. Six years after the transplant surgery, computed tomographic evaluation confirmed the presence of a 2.8-cm-diameter solid mass in the lower pole of the allograft. Partial allograft nephrectomy was performed, and the margin surrounding the normal parenchyma was resected. The serum level of creatinine did not decrease. Here, we report a case of renal cell carcinoma in an allograft kidney that was successfully treated with nephron-sparing surgery.
原发性恶性肿瘤的发生是器官移植令人苦恼的并发症。然而,同种异体肾移植中出现原发性肾细胞癌的情况较为罕见。一名60岁男性接受了来自配偶供体的活体肾移植。移植手术后六年,计算机断层扫描评估证实同种异体肾下极存在一个直径2.8厘米的实性肿块。进行了部分同种异体肾切除术,并切除了正常实质周围的边缘组织。血清肌酐水平未下降。在此,我们报告一例同种异体肾肾细胞癌病例,该病例通过保留肾单位手术成功治疗。