Yokouchi Masahiro, Arishima Yoshiya, Nagano Satoshi, Shimada Hirofumi, Nakamura Shunsuke, Setoguchi Takao, Kawamura Ichiro, Ishidou Yasuhiro, Komiya Setsuro
Associate Professor, Department of Orthopaedic Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Orthopedist, Department of Orthopaedic Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
J Foot Ankle Surg. 2016 Mar-Apr;55(2):306-9. doi: 10.1053/j.jfas.2014.09.023. Epub 2014 Dec 5.
Giant cell tumor of the bone is a benign, but locally aggressive, primary bone tumor of unknown origin. It most commonly occurs in the long bones and is only rarely found in the phalangeal bones, such as the distal phalanx of the foot. In our review of English-language published studies, only 4 other cases of giant cell tumor involving the distal phalangeal bone of the foot had been reported to date. We report a case of giant cell tumor arising in the distal phalanx of the fourth toe in a 28-year-old female. Although bisphosphonate therapy was administered, the tumor showed highly aggressive behavior with ulceration of the overlying skin, and the patient underwent phalangeal amputation 1.5 months after diagnosis.
骨巨细胞瘤是一种起源不明的良性但具有局部侵袭性的原发性骨肿瘤。它最常发生于长骨，很少见于趾骨，如足的远节趾骨。在我们对已发表的英文研究的回顾中，迄今为止仅报道了另外4例累及足远节趾骨的骨巨细胞瘤病例。我们报告1例28岁女性第四趾远节趾骨发生的骨巨细胞瘤。尽管给予了双膦酸盐治疗，但肿瘤表现出高度侵袭性行为，伴有覆盖皮肤溃疡，患者在诊断后1.5个月接受了趾骨截肢术。
