Kustermann Andreas, Möbius Cornelia, Oberstein Timo, Müller Helge H, Kornhuber Johannes
Department of Psychiatry and Psychotherapy, Friedrich-Alexander University of Erlangen-Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany.
Department of Neurology, Friedrich-Alexander University of Erlangen-Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany.
Ann Gen Psychiatry. 2014 Dec 4;13(1):37. doi: 10.1186/s12991-014-0037-8. eCollection 2014.
Originally developed for the treatment of epilepsy, pregabalin has become a compound with a wide spectrum of indications comprising anxiety disorders and chronic pain and is therefore largely prescribed. Thus, it is important for clinicians to be aware of rare, but serious adverse effects. The following report illustrates the case of a 20-year-old male with a severe depressive syndrome following pregabalin medication which even led to a suicide attempt.
普瑞巴林最初是为治疗癫痫而研发的，现已成为一种具有广泛适应症的化合物，包括焦虑症和慢性疼痛，因此被大量处方使用。所以，临床医生了解其罕见但严重的不良反应很重要。以下报告讲述了一名20岁男性在服用普瑞巴林后出现严重抑郁综合征，甚至企图自杀的病例。
