体外循环冠状动脉搭桥手术前后勃起功能障碍的评估。
Evaluations of erectile dysfunction before and after on-pump coronary artery bypass graft surgery.
作者信息
ZiabakhshTabary Shervin, Mokhtari-Esbuie Farzad, Fazli Mehran
机构信息
Cardiac Surgery Department , Fatemeh Zahra Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
Mazandaran University of Medical Sciences, Sari, Iran.
出版信息
Caspian J Intern Med. 2014 Fall;5(4):209-12.
BACKGROUND
Erectile dysfunction (ED) is common in cardiovascular disease (CVD) and indicates a complication of coronary artery bypass graft surgery (CABG). This study was designed to evaluate the status of erectile dysfunction in patients with CAD before and after CABG surgery.
METHODS
We designed a prospective cohort study on male patients candidates for elective on-pump CABG between June 2006 to October 2012 in 3 hospitals in Sari, Iran (Fatemeh Zahra, Shafa and Nime-Shaban Hospitals). Patient's primary data were collected based on the International Index of Erectile Function questionnaire (IIEF-5) at baseline 6 months after surgery. The severity of dysfunction was categorized as, normal, mild to moderate and moderate to severe based on IIEF score.
RESULTS
Four hundred twenty-six male patients with mean age of 58.69±12.49 years participated in this study. 166 patients had DM (38.96%) 230 patients had hypertension (54%). 307 patients had three-vessel impairment (72.07%) and 119 patients with one or two vessel impairment (27.93%). The 15.02%, 18.07%, 23%, 31.92% and 11.97%, at baseline changed to 16.90%, 19.95%, 23.71%, 32.22% and 8.21%, at endpoint (P=0.01). Also, the mean±SD of IIEF-5 score before and after surgery was 13.95±5.44 and 14.20±5.69, respectively (P=0.001).
CONCLUSION
The result of our study shows that on-pump CABG surgery has a positive effect on the improvement of erectile dysfunction 6 months after surgery.
背景
勃起功能障碍（ED）在心血管疾病（CVD）中很常见，并且是冠状动脉搭桥术（CABG）的一种并发症。本研究旨在评估冠心病患者在CABG手术前后勃起功能障碍的状况。
方法
我们对2006年6月至2012年10月期间在伊朗萨里的3家医院（法蒂玛·扎赫拉医院、沙法医院和尼梅-沙班医院）接受择期体外循环CABG手术的男性患者进行了一项前瞻性队列研究。患者的基本数据在基线、术后6个月时根据国际勃起功能指数问卷（IIEF-5）进行收集。根据IIEF评分，功能障碍的严重程度分为正常、轻度至中度和中度至重度。
结果
426名平均年龄为58.69±12.49岁的男性患者参与了本研究。166名患者患有糖尿病（38.96%），230名患者患有高血压（54%）。307名患者有三支血管病变（72.07%），119名患者有一支或两支血管病变（27.93%）。基线时分别为15.02%、18.07%、23%、31.92%和11.97%，在终点时变为16.90%、19.95%、23.71%、32.22%和8.21%（P=0.01）。此外，手术前后IIEF-5评分的平均值±标准差分别为13.95±5.44和14.20±5.69（P=0.001）。
结论
我们的研究结果表明，体外循环CABG手术对术后6个月勃起功能障碍的改善有积极作用。
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