Sajjad M, Machulla H J, Lambrecht R M, Bakr S
Radionuclide and Cyclotron Operations Department, King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia.
Int J Rad Appl Instrum A. 1989;40(5):428-30. doi: 10.1016/0883-2889(89)90211-6.
An improved labeling procedure for 15-(p-[123I]iodophenyl)pentadecanoic acid (IPPA) is reported. The exchange labeling yield was greater than 95%. The radiochemical yield is influenced by the presence of sodium. The major advantage of this method is that very high specific activity i.e. upto 190 mCi/mg labeled IPPA can be prepared.
报道了一种改进的15-(对-[123I]碘苯基)十五烷酸(IPPA)标记方法。交换标记产率大于95%。放射化学产率受钠的存在影响。该方法的主要优点是可以制备非常高的比活度,即高达190mCi/mg的标记IPPA。