Department of Civil and Environmental Engineering, Northeastern University , 360 Huntington Avenue, Boston, Massachusetts 02115, United States.
Environ Sci Technol. 2015 Jan 6;49(1):361-8. doi: 10.1021/es504655y. Epub 2014 Dec 23.
Over 400 tons of silver nanoparticles (AgNPs) are produced annually, 30% of which are used in medical applications due to their antibacterial properties. The widespread use of AgNPs has implications over the entire life cycle of medical products, from production to disposal, including but not limited to environmental releases of nanomaterials themselves. Here a cradle-to-grave life cycle assessment from nanoparticle synthesis to end-of-life incineration was performed for a commercially available nanosilver-enabled medical bandage. Emissions were linked to multiple categories of environmental impacts, making primary use of the TRACI 2.1 impact assessment method, with specific consideration of nanosilver releases relative to all other (non-nanosilver) emissions. Modeling results suggest that (1) environmental impacts of AgNP synthesis are dominated by upstream electricity production, with the exception of life cycle ecotoxicity where the largest contributor is mining wastes, (2) AgNPs are the largest contributor to impacts of the bandage for all impact categories considered despite low AgNP loading, and (3) impacts of bandage production are several times those bandage incineration, including nanosilver releases to the environment. These results can be used to prioritize research and policy measures in order to improve the overall ecotoxicity burdens of nanoenabled products under a life cycle framework.
每年生产超过 400 吨的银纳米粒子(AgNPs),其中 30% 因其抗菌特性而应用于医疗领域。AgNPs 的广泛使用对医疗产品的整个生命周期都有影响,从生产到处置,包括但不限于纳米材料本身的环境释放。在这里,对一种市售的纳米银医用绷带进行了从纳米粒子合成到最终焚烧的全生命周期评估。排放与多种环境影响类别相关联,主要使用 TRACI 2.1 影响评估方法,并特别考虑了纳米银相对于所有其他(非纳米银)排放的释放。建模结果表明:(1)AgNP 合成的环境影响主要由上游电力生产决定,除生命周期生态毒性外,最大的贡献因素是采矿废物,(2)尽管 AgNP 负载量较低,但 AgNPs 仍是所有考虑的影响类别中绷带影响的最大贡献者,(3)绷带生产的影响是绷带焚烧的数倍,包括纳米银向环境的释放。这些结果可用于确定研究和政策措施的优先顺序,以便在生命周期框架内改善纳米增强产品的整体生态毒性负担。