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用于体内1微米光学相干断层扫描的具有光谱复合功能的双光谱仪系统。

Dual spectrometer system with spectral compounding for 1-μm optical coherence tomography in vivo.

作者信息

Cui Dongyao, Liu Xinyu, Zhang Jing, Yu Xiaojun, Ding Sun, Luo Yuemei, Gu Jun, Shum Ping, Liu Linbo

出版信息

Opt Lett. 2014 Dec 1;39(23):6727-30. doi: 10.1364/OL.39.006727.

DOI:10.1364/OL.39.006727
PMID:25490663
Abstract

1 μm axial resolution spectral domain optical coherence tomography (OCT) is demonstrated for in vivo cellular resolution imaging. Output of two superluminescent diode sources is combined to provide near infrared illumination from 755 to 1105 nm. The spectral interference is detected using two spectrometers based on a Si camera and an InGaAs camera, respectively. Spectra from the two spectrometers are combined to achieve an axial resolution of 1.27 μm in air. Imaging was conducted on zebra fish larvae to visualize cellular details.

摘要

1微米轴向分辨率的光谱域光学相干断层扫描(OCT)被用于体内细胞分辨率成像。两个超发光二极管源的输出相结合,以提供755至1105纳米的近红外照明。分别使用基于硅相机和铟镓砷相机的两台光谱仪检测光谱干涉。将两台光谱仪的光谱相结合,在空气中实现了1.27微米的轴向分辨率。对斑马鱼幼体进行成像以观察细胞细节。

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