美国HIV感染成人对抗逆转录病毒疗法的依从性。
Adherence to antiretroviral therapy among HIV-infected adults in the United States.
作者信息
Beer Linda, Skarbinski Jacek
出版信息
AIDS Educ Prev. 2014 Dec;26(6):521-37. doi: 10.1521/aeap.2014.26.6.521.
Abstract
National estimates of antiretroviral therapy (ART) adherence and adherence support services utilization are needed to inform efforts to improve the health of HIV-infected persons in the United States. In a nationally representative sample of HIV-infected adults receiving medical care, 86% self-reported taking all ART doses in the past 72 hours. Overall, 20% reported using adherence support services and 2% reported an unmet need for services. If all nonadherent persons not receiving adherence support and all persons with a self-perceived unmet need for adherence support accessed services, resources to support ∼42,673 additional persons would be needed. Factors associated with lower adherence included younger age, female gender, depression, stimulant use, binge alcohol use, greater than once-daily dosing, longer time since HIV diagnosis, and patient beliefs. Predictors of adherence are multifactorial so multiple targeted strategies to improve adherence are warranted. Providing adherence support services to all those in need may require additional resources.
摘要
需要对美国抗逆转录病毒疗法（ART）的依从性以及依从性支持服务的利用情况进行全国性评估，以便为改善美国艾滋病毒感染者的健康状况提供参考。在接受医疗护理的具有全国代表性的艾滋病毒感染成年人群样本中，86%的人自我报告在过去72小时内服用了所有抗逆转录病毒治疗药物剂量。总体而言，20%的人报告使用了依从性支持服务，2%的人报告有未满足的服务需求。如果所有未接受依从性支持的不依从者以及所有自我感觉有未满足的依从性支持需求的人都能获得服务，那么就需要额外的资源来支持约42,673人。与较低依从性相关的因素包括年龄较小、女性、抑郁、使用兴奋剂、大量饮酒、每日服药次数超过一次、艾滋病毒诊断后的时间较长以及患者的信念。依从性的预测因素是多方面的，因此有必要采取多种针对性策略来提高依从性。为所有有需要的人提供依从性支持服务可能需要额外的资源。
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