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1例采用腹腔镜多极射频消融非接触式消融术治疗的小肝细胞癌病例。

A case of small hepatocellular carcinoma treated with laparoscopic multipolar radiofrequency ablation with a no-touch ablation procedure.

作者信息

Morimoto Naoki, Isoda Norio, Watanabe Shunji, Otake Toshiya, Hirosawa Takuya, Tsukui Mamiko, Miyata Natsumi, Murayama Kozue, Iwashita Chihiro, Takaoka Yoshinari, Yamamoto Hironori

机构信息

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Jichi Medical University, Yakushiji 3311-1, Shimotsuke, Tochigi, 329-0498, Japan,

出版信息

Clin J Gastroenterol. 2014 Dec;7(6):510-5. doi: 10.1007/s12328-014-0531-1. Epub 2014 Oct 9.

DOI:10.1007/s12328-014-0531-1
PMID:25491908
Abstract

A 77-year-old man with hepatocellular carcinoma was admitted to our institution. Computed tomography revealed two nodules, one at the surface and one within the liver, ≤3 cm in diameter. We performed laparoscopic radiofrequency ablation using a bipolar system with a "no-touch ablation" procedure using multiple applicators for insertion, not into the tumor directly, but to the perimeter of the tumor. A sufficient ablated area was obtained regardless of tumor location. No operative complications were encountered and adequate therapeutic effect was achieved safely. Laparoscopic multipolar radiofrequency ablation is a feasible procedure for treating hepatocellular carcinoma.

摘要

一名77岁的肝细胞癌男性患者入住我院。计算机断层扫描显示有两个结节,一个位于肝脏表面,一个位于肝内,直径≤3厘米。我们使用双极系统进行腹腔镜射频消融,采用“非接触式消融”程序,使用多个施药器插入,不是直接插入肿瘤,而是插入肿瘤周边。无论肿瘤位置如何,均获得了足够的消融区域。未出现手术并发症,安全地实现了充分的治疗效果。腹腔镜多极射频消融是治疗肝细胞癌的一种可行方法。

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本文引用的文献

1
Histopathologic comparison of monopolar versus no-touch multipolar radiofrequency ablation to treat hepatocellular carcinoma within Milan criteria.米兰标准内肝细胞癌治疗中,单极与非接触式多极射频消融的组织病理学比较。
J Vasc Interv Radiol. 2014 Apr;25(4):599-607. doi: 10.1016/j.jvir.2013.11.025. Epub 2014 Feb 12.
2
Potential of a no-touch pincer ablation procedure for small hepatocellular carcinoma that uses a multipolar radiofrequency ablation system: An experimental animal study.采用多极射频消融系统的无接触钳夹消融术治疗小肝细胞癌的潜力:一项实验动物研究。
Hepatol Res. 2014 Nov;44(12):1234-40. doi: 10.1111/hepr.12240. Epub 2014 Jan 7.
3
索拉非尼联合射频消融治疗早期小肝癌的临床疗效及相关机制
Oncol Lett. 2016 Aug;12(2):951-955. doi: 10.3892/ol.2016.4694. Epub 2016 Jun 9.
Efficacy and long-term outcomes of radiofrequency ablation in the elderly with hepatocellular carcinoma.
射频消融治疗老年肝细胞癌的疗效及长期预后。
Hepatol Res. 2014 Oct;44(11):1095-101. doi: 10.1111/hepr.12233. Epub 2013 Oct 25.
4
Endoscopic versus open radiofrequency ablation for treatment of small hepatocellular carcinoma.内镜与开放式射频消融治疗小肝癌的比较。
World J Surg. 2013 Mar;37(3):597-601. doi: 10.1007/s00268-012-1868-6.
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The laparoscopic approach for radiofrequency ablation of hepatocellular carcinoma--indication, technique and results.腹腔镜射频消融治疗肝细胞癌的适应证、技术和结果。
Langenbecks Arch Surg. 2013 Jan;398(1):47-53. doi: 10.1007/s00423-012-1018-5. Epub 2012 Oct 24.
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Clinical effectiveness of bipolar radiofrequency ablation for small liver cancers.双极射频消融治疗小肝癌的临床疗效。
J Gastroenterol. 2013 Jul;48(7):874-83. doi: 10.1007/s00535-012-0685-x. Epub 2012 Oct 10.
7
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J Cancer Res Ther. 2011 Oct-Dec;7(4):463-75. doi: 10.4103/0973-1482.92023.
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Ann Ital Chir. 2011 Nov-Dec;82(6):457-63.
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