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自恋型人格障碍的大脑结构:一项基于体素的形态测量学和弥散张量成像的初步研究。

Brain structure in narcissistic personality disorder: a VBM and DTI pilot study.

机构信息

Department of Psychiatry and Psychotherapy, Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany.

Medical Physics Group, Institute of Diagnostic and Interventional Radiology, Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany.

出版信息

Psychiatry Res. 2015 Feb 28;231(2):184-6. doi: 10.1016/j.pscychresns.2014.11.001. Epub 2014 Nov 8.

Abstract

We analysed T1-weighted MRI scans using voxel-based morphometry (VBM) and tract-based spatial statistics (TBBS) on diffusion tensor images (DTI) in narcissistic personality disorder (NaPD) patients and healthy controls. Grey matter deficits include right prefrontal and bilateral medial prefrontal/anterior cingulate cortices, and decreased fractional anisotropy in right frontal lobe white matter.

摘要

我们使用基于体素的形态测量学(VBM)和基于弥散张量成像(DTI)的束路径空间统计学(TBBS)对自恋型人格障碍(NaPD)患者和健康对照者的 T1 加权 MRI 扫描进行了分析。灰质缺陷包括右侧前额叶和双侧内侧前额叶/前扣带皮质,以及右侧额叶白质的各向异性分数降低。

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