如何使用脱细胞真皮基质(ADM)和植入物进行保留乳头乳晕复合体(NAC)的乳房切除术。

How to perform a NAC sparing mastectomy using an ADM and an implant.

作者信息

Gunnarsson Gudjon Leifur, Børsen-Koch Mikkel, Wamberg Peter, Thomsen Jørn Bo

机构信息

1 Department of Plastic Surgery, Telemark Hospital, Skien, Norway ; 2 Department of Plastic Surgery, Lillebaelt Hospital/Odense University Hospital, Kabbeltoft 25, 7100 Vejle, Denmark ; 3 Department of Surgery Section for Breast Surgery, Lillebaelt Hospital, Kabbeltoft 25, 7100 Vejle, Denmark ; 4 Department of Plastic Surgery, Lillebaelt Hospital/Odense University Hospital, Kabbeltoft 25, 7100 Vejle, Denmark ; 5 Institute of Regional Health Services Research Center Lillebaelt Faculty of Health Sciences University of Southern Denmark, Denmark.

出版信息

Gland Surg. 2014 Nov;3(4):252-7. doi: 10.3978/j.issn.2227-684X.2014.08.01.

Abstract

BACKGROUND

Preservation of the nipple areolar complex (NAC) provides the optimal conditions for immediate breast reconstruction (IBR). Growing evidence suggests the oncological safety of nipple sparing mastectomy (NSM) when neither NAC nor skin is affected by tumor. This paper presents our initial experience performing NSM and IBR in a selected group of patients through the inframammary incision assisted by hydrodissection.

MATERIAL AND METHODS

The study includes 20 healthy women, aged 23-53, and referred for bilateral risk-reducing mastectomy. NSM was carried out using inframammary crease incision assisted by hydrodissection followed by IBR with an acellular dermal matrix (ADM) and an implant as presented in the attached video. Exclusions criteria were hypertension, diabetes, active smoking and previous chest radiation therapy. Data was collected retrospectively.

RESULTS

We achieved the reconstructive goal for all 40 breasts (100%). There were no cases of NAC necrosis. Minor complications were registered in two reconstructions (5%), including one case of small partial necrosis and one case of wound dehiscence. The median follow-up was 13 months (range, 1-32 months).

CONCLUSIONS

Bilateral risk-reducing NSM and IBR can be successfully achieved through an inframammary crease incision assisted by hydrodissection. Patient selection is the key to a successful outcome.

摘要

背景

保留乳头乳晕复合体(NAC)为即刻乳房重建(IBR)提供了最佳条件。越来越多的证据表明,当NAC和皮肤均未受肿瘤影响时,保乳乳头切除术(NSM)在肿瘤学上是安全的。本文介绍了我们通过乳房下皱襞切口在水分离辅助下对一组选定患者进行NSM和IBR的初步经验。

材料与方法

该研究纳入了20名年龄在23 - 53岁之间、因双侧预防性乳房切除术前来就诊的健康女性。采用乳房下皱襞切口并在水分离辅助下进行NSM,随后如随附视频所示,使用脱细胞真皮基质(ADM)和植入物进行IBR。排除标准为高血压、糖尿病、当前吸烟以及既往胸部放疗史。数据进行回顾性收集。

结果

我们成功实现了所有40个乳房(100%)的重建目标。没有NAC坏死病例。在两次重建手术(5%)中出现了轻微并发症,包括1例小面积局部坏死和1例伤口裂开。中位随访时间为13个月(范围1 - 32个月)。

结论

通过乳房下皱襞切口在水分离辅助下可成功实现双侧预防性NSM和IBR。患者选择是成功的关键。

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