Hughes S, Smith M E
Department of Physiology, Medical School, University of Birmingham, U.K.
Neurosci Lett. 1989 Aug 28;103(2):169-73. doi: 10.1016/0304-3940(89)90570-3.
beta-Endorphin and alpha-melanotropin immunoreactivity was detected in motor nerves in histological sections of murine skeletal muscle, using the peroxidase-antiperoxidase technique. In mice of the wobbler strain, which can inherit motoneurone disease, a significantly higher proportion of the intramuscular nerves in soleus, extensor digitorum longus and diaphragm muscles of the diseased mice were immunoreactive than in the corresponding muscles of their healthy littermates.
采用过氧化物酶-抗过氧化物酶技术，在小鼠骨骼肌组织切片的运动神经中检测到β-内啡肽和α-促黑素免疫反应性。在可遗传运动神经元疾病的震颤小鼠品系中，患病小鼠比目鱼肌、趾长伸肌和膈肌中免疫反应性肌内神经的比例显著高于其健康同窝小鼠相应肌肉中的比例。
