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使用Flow-diverting Silk®支架治疗复杂颅内动脉瘤。对32例连续患者的分析。

Treatment of complex intracranial aneurysms using flow-diverting silk® stents. An analysis of 32 consecutive patients.

作者信息

Buyukkaya Ramazan, Kocaeli Hasan, Yildirim Nalan, Cebeci Hakan, Erdogan Cüneyt, Hakyemez Bahattin

机构信息

Department of Radiology, Düzce University Medical School; Düzce, Turkey -

Department of Neurosurgery, Uludag University Medical School; Bursa, Turkey.

出版信息

Interv Neuroradiol. 2014 Dec;20(6):729-35. doi: 10.15274/INR-2014-10070. Epub 2014 Dec 5.

Abstract

This study describes the peri-procedural and late complications and angiographic follow-up results of 32 patients with 34 complex aneurysms treated with flow diverter Silk stents in a single centre. In this retrospective study, 40 Silk stents (SS) were implanted in 34 complex intracranial aneurysms in 32 patients. In our series, 20 (58.8%) carotid-ophthalmic internal carotid artery (ICA), six (17.6%) cavernous ICA, two (5.9%) supraclinoid ICA, two (5.9%) petrosal ICA (the same patient- bilateral) and four (11.8%) posterior circulation aneurysms were treated. One of the posterior circulation lesions was a fenestrated-type aneurysm. Twenty wide-necked, saccular; eight neck remnant; four fusiform and two blister-like aneurysms were included in our series. SS were successfully implanted in all patients (100%). Misdeployment occurred in 17.6% of patients. In two of these patients adequate stent openness was achieved via Hyperglide balloon dilatation. Coil embolization in addition to SS placement was utilized in four aneurysms. One patient (3%) experienced transient morbidity due to a thromboembolic event and there was one mortality (3%) due to remote intraparenchymal haemorrhage. Complete occlusion of 27/33 (81.8 %) and 29/33 (87.9 %) aneurysms was achieved six and 12 months after the procedure, respectively. In-stent intimal hyperplasia was detected in 6.1 % patients. Flow-diverter Silk stent implantation is an effective method of treating complex aneurysms with acceptable mortality and morbidity rates. Complete occlusion is achieved in most of the complex aneurysms.

摘要

本研究描述了在单一中心接受血流导向丝支架治疗的32例患者34个复杂动脉瘤的围手术期和晚期并发症以及血管造影随访结果。在这项回顾性研究中,32例患者的34个复杂颅内动脉瘤植入了40枚丝支架(SS)。在我们的系列研究中,治疗了20个(58.8%)颈内动脉眼段、6个(17.6%)海绵窦段颈内动脉、2个(5.9%)床突上段颈内动脉、2个(5.9%)岩骨段颈内动脉(同一患者双侧)和4个(11.8%)后循环动脉瘤。其中1个后循环病变为开窗型动脉瘤。我们的系列研究包括20个宽颈囊状动脉瘤、8个残颈动脉瘤、4个梭形动脉瘤和2个水泡样动脉瘤。所有患者(100%)均成功植入SS。17.6%的患者发生支架误释放。其中2例患者通过Hyperglide球囊扩张实现了支架充分打开。4个动脉瘤在放置SS的基础上还进行了弹簧圈栓塞。1例患者(3%)因血栓栓塞事件出现短暂性发病,1例患者(3%)因远处脑实质内出血死亡。术后6个月和12个月分别有27/33(81.8%)和29/33(87.9%)的动脉瘤实现完全闭塞。6.1%的患者检测到支架内内膜增生。血流导向丝支架植入术是治疗复杂动脉瘤的一种有效方法,死亡率和发病率可接受。大多数复杂动脉瘤可实现完全闭塞。

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