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本文引用的文献

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Neurosurgery. 2018 Apr 1;82(4):491-496. doi: 10.1093/neuros/nyx226.
2
In-stent Stenosis after p64 Flow Diverter Treatment.支架内狭窄(p64 血流导向装置治疗后)。
Clin Neuroradiol. 2018 Dec;28(4):563-568. doi: 10.1007/s00062-017-0591-y. Epub 2017 May 9.
3
Long-Term Clinical and Angiographic Outcomes Following Pipeline Embolization Device Treatment of Complex Internal Carotid Artery Aneurysms: Five-Year Results of the Pipeline for Uncoilable or Failed Aneurysms Trial.使用密网支架治疗复杂颈内动脉动脉瘤后的长期临床和血管造影结果:不可栓塞或栓塞失败动脉瘤的密网支架试验五年结果
Neurosurgery. 2017 Jan 1;80(1):40-48. doi: 10.1093/neuros/nyw014.
4
Single-stage endovascular treatment of multiple intracranial aneurysms with combined endovascular techniques: is it safe to treat all at once?采用联合血管内技术对多发性颅内动脉瘤进行单阶段血管内治疗:一次性治疗所有动脉瘤是否安全?
J Neurointerv Surg. 2017 Nov;9(11):1069-1074. doi: 10.1136/neurintsurg-2016-012745. Epub 2016 Nov 14.
5
Spontaneous subarachnoid haemorrhage.自发性蛛网膜下腔出血。
Lancet. 2017 Feb 11;389(10069):655-666. doi: 10.1016/S0140-6736(16)30668-7. Epub 2016 Sep 13.
6
Flow Diversion for Intracranial Aneurysm Management: A New Standard of Care.颅内动脉瘤治疗中的血流导向:一种新的治疗标准
Neurotherapeutics. 2016 Jul;13(3):582-9. doi: 10.1007/s13311-016-0436-4.
7
Endovascular treatment of intracranial aneurysms using the Pipeline Flex embolization device: a case series of 30 consecutive patients.使用Pipeline Flex栓塞装置对颅内动脉瘤进行血管内治疗:30例连续病例系列
J Neurointerv Surg. 2016 Apr;8(4):396-401. doi: 10.1136/neurintsurg-2015-011669. Epub 2015 Mar 13.
8
Treatment of complex intracranial aneurysms using flow-diverting silk® stents. An analysis of 32 consecutive patients.使用Flow-diverting Silk®支架治疗复杂颅内动脉瘤。对32例连续患者的分析。
Interv Neuroradiol. 2014 Dec;20(6):729-35. doi: 10.15274/INR-2014-10070. Epub 2014 Dec 5.
9
The durability of endovascular coiling versus neurosurgical clipping of ruptured cerebral aneurysms: 18 year follow-up of the UK cohort of the International Subarachnoid Aneurysm Trial (ISAT).破裂性脑动脉瘤血管内栓塞与神经外科夹闭术的耐久性:国际蛛网膜下腔动脉瘤试验(ISAT)英国队列的18年随访
Lancet. 2015 Feb 21;385(9969):691-7. doi: 10.1016/S0140-6736(14)60975-2. Epub 2014 Oct 28.
10
Thromboembolic complications with Pipeline Embolization Device placement: impact of procedure time, number of stents and pre-procedure P2Y12 reaction unit (PRU) value.使用Pipeline栓塞装置进行血栓栓塞并发症:手术时间、支架数量及术前P2Y12反应单位(PRU)值的影响
J Neurointerv Surg. 2015 Mar;7(3):217-21. doi: 10.1136/neurintsurg-2014-011111. Epub 2014 Feb 19.

采用Pipeline栓塞术分期治疗双侧颈内动脉动脉瘤的中期随访

Mid-term follow-up of staged bilateral internal carotid artery aneurysm treatment with Pipeline embolization.

作者信息

Tejada Juan G, Lopez Gloria Vv, Koovor Jerry Me, Riley Kalen, Martinez Mesha

机构信息

Eskenazi Health, Indianapolis, USA.

University of Iowa, Iowa City, USA.

出版信息

Interv Neuroradiol. 2019 Dec;25(6):664-670. doi: 10.1177/1591019919853586. Epub 2019 Jun 3.

DOI:10.1177/1591019919853586
PMID:31159632
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6838859/
Abstract

BACKGROUND

Endovascular treatment of large complex morphology aneurysms is challenging. High recanalization rates have been reported with techniques such as stent-assisted coiling and balloon-assisted coiling. Flow diverter devices have been introduced to improve efficacy outcomes and recanalization rates. Thromboembolic complications and in-device stenosis are certainly more worrisome when treatment of bilateral internal carotid arteries has been performed. This study aimed to report our experience with mid-term imaging follow-up of staged bilateral Pipeline embolization device placement for the treatment of bilateral internal carotid artery aneurysms.

METHODS

We reviewed the clinical, angiographic, and follow-up imaging data in all consecutive patients treated with bilateral internal carotid artery aneurysms who underwent elective Pipeline embolization.

RESULTS

Six female patients were treated, harboring a total of 13 aneurysms. Of these, 60% were asymptomatic. Diplopia and headache were the most common symptoms. The most common location was the paraclinoid segment (6/13), including by cavernous segment (4/13) and ophthalmic segment (2/13). Successful delivery of the device was achieved in 12 cases. Difficult distal access precluded the deployment of the device in one case. The treatment was always staged with at least eight weeks' difference between the two procedures. All aneurysm necks were covered completely. There were no periprocedural complications. Angiographic follow-up ranged between 3 and 12 months, and computed tomography angiogram follow-up ranged between 2 and 24 months. Complete aneurysm occlusion was achieved in all cases.

CONCLUSION

In our series, Pipeline deployment for the treatment of bilateral internal carotid artery aneurysms in a staged fashion is safe and feasible. Mid-term imaging follow-up showed permanent occlusion of all the treated aneurysms.

摘要

背景

大型复杂形态动脉瘤的血管内治疗具有挑战性。据报道,支架辅助弹簧圈栓塞和球囊辅助弹簧圈栓塞等技术的再通率较高。血流导向装置已被引入以改善疗效和再通率。当双侧颈内动脉均接受治疗时,血栓栓塞并发症和装置内狭窄无疑更令人担忧。本研究旨在报告我们对分期双侧植入Pipeline栓塞装置治疗双侧颈内动脉动脉瘤的中期影像随访经验。

方法

我们回顾了所有接受选择性Pipeline栓塞治疗双侧颈内动脉动脉瘤的连续患者的临床、血管造影和随访影像数据。

结果

6例女性患者接受了治疗,共患有13个动脉瘤。其中,60%无症状。复视和头痛是最常见的症状。最常见的部位是床突旁段(6/13),包括海绵窦段(4/13)和眼段(2/13)。12例成功植入装置。1例因远端通路困难未能植入装置。治疗总是分期进行,两次手术之间至少间隔8周。所有动脉瘤颈均被完全覆盖。术中无并发症。血管造影随访时间为3至12个月,计算机断层血管造影随访时间为2至24个月。所有病例均实现了动脉瘤完全闭塞。

结论

在我们的系列研究中,分期植入Pipeline治疗双侧颈内动脉动脉瘤是安全可行的。中期影像随访显示所有治疗的动脉瘤均永久性闭塞。