翻译结果：实验性创伤性脑损伤的生物学与行为学理解。
Found in translation: Understanding the biology and behavior of experimental traumatic brain injury.
作者信息
Bondi Corina O, Semple Bridgette D, Noble-Haeusslein Linda J, Osier Nicole D, Carlson Shaun W, Dixon C Edward, Giza Christopher C, Kline Anthony E
机构信息
Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA, United States; Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, PA, United States; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, United States; Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA, United States.
Neurological Surgery and the Graduate Program in Physical Medicine & Rehabilitation Science, University of California, San Francisco, San Francisco, CA, United States; Department of Medicine (Royal Melbourne Hospital), University of Melbourne, Parkville, VIC, Australia.
出版信息
Neurosci Biobehav Rev. 2015 Nov;58:123-46. doi: 10.1016/j.neubiorev.2014.12.004. Epub 2014 Dec 10.
The aim of this review is to discuss in greater detail the topics covered in the recent symposium entitled "Traumatic brain injury: laboratory and clinical perspectives," presented at the 2014 International Behavioral Neuroscience Society annual meeting. Herein, we review contemporary laboratory models of traumatic brain injury (TBI) including common assays for sensorimotor and cognitive behavior. New modalities to evaluate social behavior after injury to the developing brain, as well as the attentional set-shifting test (AST) as a measure of executive function in TBI, will be highlighted. Environmental enrichment (EE) will be discussed as a preclinical model of neurorehabilitation, and finally, an evidence-based approach to sports-related concussion will be considered. The review consists predominantly of published data, but some discussion of ongoing or future directions is provided.
本综述的目的是更详细地讨论在2014年国际行为神经科学学会年会上举办的题为“创伤性脑损伤：实验室与临床视角”的近期研讨会上所涵盖的主题。在此，我们回顾创伤性脑损伤（TBI）的当代实验室模型，包括感觉运动和认知行为的常用检测方法。将重点介绍评估发育中大脑损伤后社交行为的新方法，以及作为TBI执行功能测量指标的注意力转换测试（AST）。环境富集（EE）将作为神经康复的临床前模型进行讨论，最后，将考虑一种基于证据的与运动相关脑震荡的处理方法。本综述主要由已发表的数据组成，但也提供了一些对正在进行或未来方向的讨论。
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