Töröcsik A, Chaudhry I A, Nagashima H, Kinjo M, Duncalf D, Nagashima R, Foldes F F, Goldiner P L, Vizi E S
Department of Pharmacology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest.
Arch Int Pharmacodyn Ther. 1989 May-Jun;299:247-53.
The postsynaptic antimuscarinic properties of different nondepolarizing muscle relaxants were compared with their postsynaptic antinicotinic effect. d-Tubocurarine, pipecuronium and vecuronium were the most selective antagonists on postsynaptic nicotinic receptors. Gallamine, diadonium and Duador (RGH-4201) had relatively greater effect on postsynaptic muscarinic receptors. Therefore, much less side effect is expected to occur when pipecuronium, d-tubocurarine or vecuronium are used.
