Ramond M J, Valla D, Mosnier J F, Degott C, Bernuau J, Rueff B, Benhamou J P
Service d'Hépatologie, Unité de Recherches de Physiopathologie Hépatique (INSERM), Clichy, France.
Hepatology. 1989 Oct;10(4):488-93. doi: 10.1002/hep.1840100415.
In 27 patients who had bled from esophagogastric varices, large-sized and/or actively bleeding gastric varices were endoscopically obturated with the tissue adhesive butyl cyanoacrylate. Active bleeding was stopped in six patients. Rebleeding occurred in 10 patients; in four patients, rebleeding was due to ruptured gastric varices, occurred early and was successfully treated by reinjection of gastric varices; in one patient, rebleeding was attributed to ulceration on an injected gastric varix. Eight patients died: two of rebleeding (from esophageal varices or undetermined source), four of sepsis and/or liver failure and two at home of undetermined cause. No specific complication due to injection of gastric varices was observed. The results obtained in this series of patients with gastric varices obturated by injection of butyl cyanoacrylate are much more satisfactory than those obtained in previously published series of patients with gastric varices treated by injection of sclerosants.
在27例食管胃静脉曲张出血的患者中，通过内镜用组织粘合剂氰基丙烯酸正丁酯闭塞大尺寸和/或活动性出血的胃静脉曲张。6例患者活动性出血停止。10例患者再次出血；4例患者再次出血是由于胃静脉曲张破裂，发生较早，通过再次注射胃静脉曲张成功治疗；1例患者再次出血归因于注射的胃静脉曲张溃疡。8例患者死亡：2例死于再次出血（食管静脉曲张或不明原因），4例死于败血症和/或肝功能衰竭，2例在家中死因不明。未观察到因注射胃静脉曲张导致的特定并发症。本系列通过注射氰基丙烯酸正丁酯闭塞胃静脉曲张的患者所获得的结果比先前发表的通过注射硬化剂治疗胃静脉曲张的系列患者所获得的结果要令人满意得多。
