Li Ye, Song Qing-Wei, Sun Mei-Yu, Wang He-Qing, Wang Sheng, Wei Qiang, Liu Jing-Hong, Tian Shi-Feng, Tong Zi-Bin, Liu Ai-Lian
Department of Radiology, The First Affiliated Hospital of Dalian Medical University, No.222 Zhongshan Road, Xigang District, Dalian, 116011, Liaoning, China.
Abdom Imaging. 2015 Aug;40(6):1733-41. doi: 10.1007/s00261-014-0314-7.
To evaluate the feasibility of enhanced T2 star-weighted angiography (ESWAN) in differentiating endometrial from non-endometrial cysts.
Forty-nine patients with 60 histopathologically proven ovarian cystic lesions underwent pelvic MRI including T1-weighted imaging (T1WI), T2-weighted imaging (T2WI), liver acquisition with volume acceleration, and ESWAN. Ovarian cystic lesions were divided into endometrial cysts (group 1; n = 28), pyosalpinx and hydrosalpinx (group 2; n = 13), and ovarian cystic and cystic-solid tumors (group 3; n = 19). R2* (effective transverse relaxation rate) values were measured and pairwise comparison of the R2* values among the three groups was made using Kruskal-Wallis test. Receiver operating characteristic curves were used to calculate cutoff values and performance of R2* values for distinguishing among groups. T1WI signal intensity and R2* value were also compared using area under curve values.
R2* values for group 1 were statistically higher than groups 2 and 3 (15.37, 1.40, and 1.79 Hz, respectively; P < 0.001). The cutoff value for R2* was 7.43 Hz with a sensitivity, specificity, PPV, NPV, and accuracy of 96.43, 87.50, 87.10, 96.55, and 91.67%, respectively. There was no significant difference between the R2* value and T1WI in diagnosing endometrial cysts.
The R2* value provides an effective way to discriminate endometrial cysts from other ovarian cystic lesions.
评估增强T2*加权血管造影（ESWAN）在鉴别子宫内膜囊肿与非子宫内膜囊肿方面的可行性。
49例患有60个经组织病理学证实的卵巢囊性病变的患者接受了盆腔MRI检查，包括T1加权成像（T1WI）、T2加权成像（T2WI）、肝脏容积加速采集和ESWAN。卵巢囊性病变分为子宫内膜囊肿（第1组；n = 28）、输卵管积脓和输卵管积水（第2组；n = 13）以及卵巢囊性和囊实性肿瘤（第3组；n = 19）。测量R2*（有效横向弛豫率）值，并使用Kruskal-Wallis检验对三组之间的R2值进行两两比较。采用受试者操作特征曲线计算区分各组的R2值的截断值和性能。还使用曲线下面积值比较T1WI信号强度和R2*值。
第1组的R2值在统计学上高于第2组和第3组（分别为15.37、1.40和1.79 Hz；P < 0.001）。R2的截断值为7.43 Hz，敏感性、特异性、阳性预测值、阴性预测值和准确性分别为96.43%、87.50%、87.10%、96.55%和91.67%。在诊断子宫内膜囊肿方面，R2*值与T1WI之间没有显著差异。
R2*值为鉴别子宫内膜囊肿与其他卵巢囊性病变提供了一种有效的方法。
