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是时候重新思考我们对接受择期腹疝修补术的透析患者的管理了吗?对美国外科医师学会国家外科质量改进计划(ACS NSQIP)数据库的分析。

Is it time to rethink our management of dialysis patients undergoing elective ventral hernia repair? Analysis of the ACS NSQIP database.

作者信息

Tam S F, Au J T, Chung P J, Duncan A, Alfonso A E, Sugiyama G

机构信息

SUNY Downstate College of Medicine, Brooklyn, NY, USA.

Department of Surgery, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, 11203, NY, USA.

出版信息

Hernia. 2015 Oct;19(5):827-33. doi: 10.1007/s10029-014-1332-7. Epub 2014 Dec 11.

Abstract

PURPOSE

The number of patients on chronic dialysis is steadily increasing each year. There is little data that describes the outcomes in dialysis patients following elective ventral hernia repair, one of the most common general surgery procedures. Our objective was to compare the mortality and morbidity rates in dialysis versus nondialysis patients following elective ventral hernia repair.

METHODS

We analysed the ACS NSQIP database to identify patients that underwent elective ventral hernia repair from 2005 to 2010. Univariate analysis and multivariate logistic regression was performed on all patients included. The main outcome variables were mortality and morbidity, length of hospital stay, and return to the operating room.

RESULTS

Following elective ventral hernia repair, dialysis patients were more likely to die within 30 days or experience at least one morbidity. Dialysis patients were more likely to experience an infectious, pulmonary or vascular complication. Patients on dialysis also had a 2-fold greater risk of returning to the operating room within 30 days and stayed in the hospital an average of 1.3 days longer than nondialysis patients. Similar results were found after adjustment for demographics and comorbidities using multivariable logistic regression.

CONCLUSION

This is one of the largest studies demonstrating the outcomes of a specific general surgery procedure in dialysis patients. Chronic dialysis prior to elective ventral hernia repair is associated with an increased risk of 30-day mortality, morbidity, and return to the operating room. Dialysis patients are susceptible to infectious, pulmonary, and vascular post-operative complications.

摘要

目的

每年接受慢性透析治疗的患者数量在稳步增加。对于透析患者在接受择期腹疝修补术后的预后情况,相关数据较少,而腹疝修补术是最常见的普通外科手术之一。我们的目的是比较透析患者和非透析患者在接受择期腹疝修补术后的死亡率和发病率。

方法

我们分析了美国外科医师学会国家外科质量改进计划(ACS NSQIP)数据库,以确定2005年至2010年期间接受择期腹疝修补术的患者。对纳入的所有患者进行单因素分析和多因素逻辑回归分析。主要结局变量包括死亡率、发病率、住院时间和重返手术室情况。

结果

在接受择期腹疝修补术后,透析患者在30天内死亡或发生至少一种并发症的可能性更高。透析患者更易发生感染、肺部或血管并发症。透析患者在30天内重返手术室的风险也高出2倍,且平均住院时间比非透析患者长1.3天。在使用多因素逻辑回归对人口统计学和合并症进行调整后,发现了类似结果。

结论

这是规模最大的研究之一,展示了透析患者接受特定普通外科手术后的预后情况。择期腹疝修补术前的慢性透析与30天死亡率、发病率及重返手术室的风险增加相关。透析患者易发生术后感染、肺部和血管并发症。

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