Metzman R, Anand A, DeGiulio P A, Knisely A S
Department of Pathology, Pennsylvania Hospital, Philadelphia.
J Pediatr Gastroenterol Nutr. 1989 Jul;9(1):112-4.
A hydropic premature infant with intrauterine growth retardation died at 4 days of age and was found at necropsy to have advanced liver disease. Clinical and serologic findings in mother and infant were consistent with recent parvovirus B19 infection. Parvovirus can cause fetal liver disease in animals, and some instances of congenital hepatic dysfunction in man may be due to intrauterine parvovirus B19 infection.
一名患有宫内生长迟缓的水肿早产儿在4日龄时死亡,尸检发现有晚期肝病。母婴的临床和血清学检查结果与近期细小病毒B19感染相符。细小病毒可在动物中引起胎儿肝病,人类的一些先天性肝功能障碍病例可能归因于宫内细小病毒B19感染。