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一名早产新生儿中与宫内细小病毒B19感染相关的肝脏疾病

Hepatic disease associated with intrauterine parvovirus B19 infection in a newborn premature infant.

作者信息

Metzman R, Anand A, DeGiulio P A, Knisely A S

机构信息

Department of Pathology, Pennsylvania Hospital, Philadelphia.

出版信息

J Pediatr Gastroenterol Nutr. 1989 Jul;9(1):112-4.

PMID:2550601
Abstract

A hydropic premature infant with intrauterine growth retardation died at 4 days of age and was found at necropsy to have advanced liver disease. Clinical and serologic findings in mother and infant were consistent with recent parvovirus B19 infection. Parvovirus can cause fetal liver disease in animals, and some instances of congenital hepatic dysfunction in man may be due to intrauterine parvovirus B19 infection.

摘要

一名患有宫内生长迟缓的水肿早产儿在4日龄时死亡,尸检发现有晚期肝病。母婴的临床和血清学检查结果与近期细小病毒B19感染相符。细小病毒可在动物中引起胎儿肝病,人类的一些先天性肝功能障碍病例可能归因于宫内细小病毒B19感染。

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引用本文的文献

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Human Parvoviruses.人类细小病毒
Clin Microbiol Rev. 2017 Jan;30(1):43-113. doi: 10.1128/CMR.00040-16.
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Neonatal hemochromatosis.新生儿血色沉着症
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Parvovirus B19 during pregnancy: a review.妊娠期间的细小病毒B19:综述
J Prenat Med. 2010 Oct;4(4):63-6.
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Parvovirus B19-induced apoptosis of hepatocytes.细小病毒B19诱导的肝细胞凋亡。
J Virol. 2004 Jul;78(14):7775-83. doi: 10.1128/JVI.78.14.7775-7783.2004.
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Classification and genetic features of neonatal haemochromatosis: a study of 27 affected pedigrees and molecular analysis of genes implicated in iron metabolism.新生儿血色病的分类及遗传特征:对27个受累家系的研究及与铁代谢相关基因的分子分析
J Med Genet. 2001 Sep;38(9):599-610. doi: 10.1136/jmg.38.9.599.
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Infection with Parvovirus B19.感染细小病毒B19。
Curr Infect Dis Rep. 1999 Aug;1(3):273-278. doi: 10.1007/s11908-999-0030-6.
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Hepatic morphology and iron quantitation in perinatal hemochromatosis. Comparison with a large perinatal control population, including cases with chronic liver disease.围产期血色病的肝脏形态学与铁定量分析。与大型围产期对照人群的比较,包括慢性肝病病例。
Am J Pathol. 1993 Nov;143(5):1312-25.
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Parvovirus B19 infection in pregnancy.妊娠期细小病毒B19感染
Arch Dis Child Fetal Neonatal Ed. 1994 Jul;71(1):F4-5. doi: 10.1136/fn.71.1.f4.