Dominguete Matheus Henrique Lopes, Dominguette Alexandre Augusto Sarto, Matos Bruno Henrique, Dominguete Paulo Roberto, León Jorge Esquiche, Oliveira Lucinei Roberto
Universidade Vale do Rio Verde (UninCor), Avenida Castelo Branco 82, Chácara das Rosas, 37410-000, Três Corações, MG, Brazil.
Faculdade de Odontologia de Ribeirão Preto (FORP/USP), Ribeirão Preto, SP, Brazil.
Case Rep Dent. 2014;2014:204258. doi: 10.1155/2014/204258. Epub 2014 Nov 23.
Central ossifying fibroma is a benign slow-growing tumor of mesenchymal origin and it tends to occur in the second and third decades of life, with predilection for women and for the mandibular premolar and molar areas. Clinically, it is a large asymptomatic tumor of aggressive appearance, with possible tooth displacement. Occasionally treated by curettage enucleation, this conservative surgical excision is showing a recurrence rate extremely low. The objective of this study was to report a case of a 44-year-old woman, presenting a very large ossifying fibroma in the mandible, which was successfully treated with curettage, and to conduct a brief literature review of this lesion, focusing on the histology, clinical behavior, and management of these uncommon lesions.
中央型骨化性纤维瘤是一种起源于间充质的良性缓慢生长肿瘤,好发于生命的第二个和第三个十年,女性多见,且好发于下颌前磨牙和磨牙区。临床上,它是一种外观侵袭性的大型无症状肿瘤,可能导致牙齿移位。偶尔通过刮除摘除术治疗,这种保守的手术切除显示复发率极低。本研究的目的是报告一例44岁女性下颌骨出现非常大的骨化性纤维瘤并成功通过刮除术治疗的病例,并对该病变进行简要文献综述,重点关注这些罕见病变的组织学、临床行为和治疗。