颌骨骨化性纤维瘤：14 例临床研究及文献复习。
Ossifying fibroma of the jaws: a clinical study of 14 cases and review of the literature.
机构信息
Department of Oral and Maxillofacial Surgery, Dental School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
出版信息
Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Aug;114(2):193-9. doi: 10.1016/j.tripleo.2011.07.033. Epub 2012 Feb 25.
OBJECTIVE
The purpose of this study was to evaluate the clinical outcomes of ossifying fibroma (OF) in a group of 14 patients treated in our clinic and discuss the management and the prognosis of this tumor.
STUDY DESIGN
The study included 14 consecutive patients with OF of the jaws with ages ranging from 7 to 55 years. Primary site distribution was maxilla (1), maxilla, maxillary sinus (1), and mandible (12). All of the patients treated by surgery (curettage, enucleation, or radical surgery).
RESULTS
The mean follow-up range was 2-18 years. All of the patients were alive and disease free.
CONCLUSIONS
OF is a benign slow-growing tumor of the jaws. Early tumors that are small or well demarcated are treated by curettage or enucleation. For aggressive tumors that show rapid enlargement, radical resection (maxillectomy or segmental mandibulectomy) is used. By either method of treatment, the recurrence rate is extremely low.
目的
本研究旨在评估在我们诊所治疗的 14 例骨化纤维瘤（OF）患者的临床疗效，并讨论该肿瘤的治疗方法和预后。
研究设计
该研究纳入了 14 例颌骨 OF 连续患者，年龄 7 至 55 岁。原发部位分布于上颌骨（1 例）、上颌骨及上颌窦（1 例）和下颌骨（12 例）。所有患者均接受手术治疗（刮除术、剜除术或根治性手术）。
结果
平均随访时间为 2-18 年。所有患者均存活且无疾病。
结论
OF 是一种良性、生长缓慢的颌骨肿瘤。早期肿瘤较小或边界清楚者行刮除术或剜除术。对于生长迅速、侵袭性较大的肿瘤，采用根治性切除术（上颌骨切除术或节段性下颌骨切除术）。通过这两种治疗方法，复发率均极低。
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