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[基于动基体DNA分子参数对伊拉克内脏利什曼病病原体与热带利什曼原虫的相似性研究]

[Similarity of the causative agent of visceral leishmaniasis from Iraq and Leishmania tropica based on the molecular parameters of kinetoplast DNA].

作者信息

Kolesnikov A A, Saf'ianova V M

出版信息

Med Parazitol (Mosk). 1989 May-Jun(3):20-2.

PMID:2550756
Abstract

Restriction analysis demonstrated that the cleavage pattern of kinetoplast DNA of visceral leishmaniasis causative agent from Iraq was similar to that of the anthroponotic cutaneous leishmaniasis causative agent Leishmania tropica, and differed from that of the kinetoplast DNA of Leishmania infantum and L. donovani, typical visceral leishmaniasis causative agents. Similarity was established both for maxi- and minicycle molecules of the kinetoplast DNA. Evolutionary relation between L. tropica and the causative agent of visceral leishmaniasis from Iraq is suggested.

摘要

限制性分析表明,来自伊拉克的内脏利什曼病病原体的动基体DNA切割模式与anthroponotic皮肤利什曼病病原体热带利什曼原虫相似,与婴儿利什曼原虫和杜氏利什曼原虫(典型的内脏利什曼病病原体)的动基体DNA不同。动基体DNA的大、小环分子均建立了相似性。提示了热带利什曼原虫与来自伊拉克的内脏利什曼病病原体之间的进化关系。

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