Rioux J A, Dereure J, Daoud W, el Kubati Y, Rageh H A, Moreno G, Pratlong F
Laboratoire d'Ecologie médicale et de Pathologie parasitaire, Faculté de Médecine, Montpellier, France.
Bull Soc Pathol Exot Filiales. 1989;82(5):658-64.
In complement to a previous survey, the authors proceed to the analysis of strains isolated from visceral human and canine leishmaniasis. Finally, among eight human strains isolated and identified with an enzymatic method, seven belong to the Leishmania donovani complex and one to the L. infantum complex. The L. donovani complex is represented by the MON-31 and MON-83 zymodem. The first one is also present in Saudi Arabia and Ethiopia. The second one, corresponding to a small variant, pleads for an intrafocal polymorphism phenomenon which was until now unknown in the L. donovani complex. The L. infantum complex is observed: 1) in sympatria with L. donovani in mountainous areas; 2) alone in the Tihama coastal plain. As for human cutaneous leishmaniasis present in the same focuses it is caused by L. tropica MON-71 and not by the above mentioned complexes.
作为之前一项调查的补充，作者对从人类和犬类内脏利什曼病中分离出的菌株进行了分析。最后，在通过酶法分离和鉴定的8株人类菌株中，7株属于杜氏利什曼原虫复合体，1株属于婴儿利什曼原虫复合体。杜氏利什曼原虫复合体由MON - 31和MON - 83酶型代表。第一种酶型也存在于沙特阿拉伯和埃塞俄比亚。第二种酶型对应一个小变异体，表明存在病灶内多态性现象，这在杜氏利什曼原虫复合体中迄今尚属未知。婴儿利什曼原虫复合体见于：1）在山区与杜氏利什曼原虫同域分布；2）在蒂哈马沿海平原单独存在。至于同一病灶中出现的人类皮肤利什曼病，是由热带利什曼原虫MON - 71引起的，而非上述复合体。
Bull Soc Pathol Exot Filiales. 1989
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