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[评估一种新型偏头痛筛查工具的诊断准确性]

[Examining the diagnostic accuracy of a new migraine screener].

作者信息

Csépány Éva, Bozsik György, Kellermann István, Hajnal Boglárka, Scheidl Erika, Palásti Ágnes, Tóth Marianna, Gyüre Tamás, Ertsey Csaba

出版信息

Ideggyogy Sz. 2014 Jul 30;67(7-8):258-68.

Abstract

BACKGROUND

Migraine affects more than 10% of the Hungarian population, causes significant disability and severely affects patients' generic and condition-specific quality of life. Despite these facts, a significant proportion of patients is not diagnosed and not treated adequately. Headache centres can provide care for only a fraction of all patients. The task of primary care providers would be greatly simplified by a reliable self-administered migraine screening questionnaire.

OBJECTIVE

To develop a short and reliable questionnaire as a migraine screening tool.

METHODS

Outpatients at the Headache Service, Department of Neurology, Semmelweis University completed a self-administered questionnaire which contained 9 yes/no questions about their headaches' characteristics. The number of 'yes' answers (the patients' total score) was evaluated in connection with the diagnosis based on the International Headache Society criteria. We calculated the sensitivity, specificity, positive and negative predictive value as well as the misclassification rate for each total score value and used these to establish the final cutoff value of the questionnaire. 306 patients (242 females, mean age 39.1 ± 13.3 years) were enrolled. The diagnosis was migraine in 244.

RESULTS

Completing the questionnaire did not pose any difficulty for the patients. At a cutoff value of 5 points the questionnaire's sensitivity was 0.96 and specificity was 0.61. The positive predictive value was 0.91 and the negative pre- dictive value was 0.81. The misclassification rate was 0.11.

DISCUSSION

Our results show that the questionnaire may help the diagnosis of migraine. In order to use it in medical practice, its further evaluation is necessary on a large representative sample of the Hungarian population.

摘要

背景

偏头痛影响超过10%的匈牙利人口,导致严重残疾,并严重影响患者的总体生活质量和特定疾病生活质量。尽管如此,仍有相当一部分患者未得到诊断和充分治疗。头痛中心只能为所有患者中的一小部分提供护理。一份可靠的自我管理偏头痛筛查问卷将大大简化初级保健提供者的工作。

目的

开发一份简短且可靠的问卷作为偏头痛筛查工具。

方法

塞梅尔维斯大学神经病学系头痛服务门诊的患者完成了一份自我管理问卷,其中包含9个关于头痛特征的是/否问题。根据国际头痛协会标准,将“是”答案的数量(患者的总分)与诊断结果相关联进行评估。我们计算了每个总分值的敏感性、特异性、阳性和阴性预测值以及错误分类率,并以此确定问卷的最终临界值。共纳入306例患者(242例女性,平均年龄39.1±13.3岁)。其中244例诊断为偏头痛。

结果

患者完成问卷没有任何困难。在临界值为5分时,问卷的敏感性为0.96,特异性为0.61。阳性预测值为0.91,阴性预测值为0.81。错误分类率为0.11。

讨论

我们的结果表明,该问卷可能有助于偏头痛的诊断。为了在医疗实践中使用它,有必要在匈牙利人口的大量代表性样本上对其进行进一步评估。

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