Lipton R B, Dodick D, Sadovsky R, Kolodner K, Endicott J, Hettiarachchi J, Harrison W
Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Neurology. 2003 Aug 12;61(3):375-82. doi: 10.1212/01.wnl.0000078940.53438.83.
Migraine is a highly prevalent and disabling illness that remains substantially undiagnosed in primary care. Because of the potential value of a screening tool, the current study was designed to establish the validity and reliability of a brief, self-administered migraine screener in patients with headache complaints in the primary care setting.
A total of 563 patients presenting for routine primary care appointments and reporting headaches in the past 3 months completed a self-administered migraine screener. All patients were then referred for an independent diagnostic evaluation by a headache expert, of whom 451 (80%) completed a full evaluation. Migraine diagnosis was assigned based on International Headache Society criteria after completing a semi-structured diagnostic interview.
Of nine diagnostic screening questions, a three-item subset of disability, nausea, and sensitivity to light provided optimum performance, with a sensitivity of 0.81 (95% CI, 0.77 to 0.85), a specificity of 0.75 (95% CI, 0.64 to 0.84), and positive predictive value of 0.93 (95% CI, 89.9 to 95.8). Test-retest reliability was good, with a kappa of 0.68 (95% CI, 0.54 to 0.82). The sensitivity and specificity of the three-item migraine screener was similar regardless of sex, age, presence of other comorbid headaches, or previous diagnostic status.
The three-item ID Migraine migraine screener was found to be a valid and reliable screening instrument for migraine headaches. Its ease of use and operating characteristics suggest that it could significantly improve migraine recognition in primary care.
偏头痛是一种高度流行且使人致残的疾病,在初级保健中仍有大量患者未被诊断出来。鉴于筛查工具的潜在价值,本研究旨在确定一种简短的、可自行填写的偏头痛筛查工具在初级保健环境中头痛患者中的有效性和可靠性。
共有563名前来进行常规初级保健预约且在过去3个月内报告有头痛症状的患者完成了一份自行填写的偏头痛筛查问卷。随后,所有患者均被转介给头痛专家进行独立诊断评估,其中451名(80%)患者完成了全面评估。在完成半结构化诊断访谈后,根据国际头痛协会的标准进行偏头痛诊断。
在九个诊断性筛查问题中,由残疾、恶心和对光敏感这三个项目组成的子集表现最佳,其敏感性为0.81(95%置信区间,0.77至0.85),特异性为0.75(95%置信区间,0.64至0.84),阳性预测值为0.93(95%置信区间,89.9至95.8)。重测信度良好,kappa值为0.68(95%置信区间,0.54至0.82)。无论性别、年龄、是否存在其他合并性头痛或既往诊断情况如何,三项偏头痛筛查问卷的敏感性和特异性均相似。
三项ID偏头痛筛查问卷被发现是一种用于偏头痛诊断的有效且可靠的筛查工具。其易用性和操作特性表明,它可以显著提高初级保健中偏头痛的识别率。