Padhi Tanmay, Pradhan Swetalina
Lepr Rev. 2014 Sep;85(3):218-23.
Restless legs syndrome (RLS) is a type of neurological disorder which presents with an uncontrollable urge to move legs and arms. It commonly affects legs more than arms. Data regarding prevalence of restless legs syndrome in leprosy are sparse. The aims and objectives of the study were to find out the prevalence of RLS in people affected by leprosy and to determine the presence and magnitude of sleep disruption in leprosy patients with RLS.
Total 143 patients diagnosed with leprosy were enrolled in the study. A diagnosis of RLS and a severity assessment were made using the criteria described by International Restless Legs Syndrome Study Group. The Pittsburgh Sleep Quality Index (PSQI) was evaluated in all those who were diagnosed with RLS.
Out of 143 patients recruited in the study, 56 (39.16%) patients were found to be suffering from RLS. Mean Pittsburgh Sleep Quality Index global score was higher (16.55), and the value was specifically higher among patients presenting with Type-2 lepra reaction (17.8) and pure neuritic leprosy (15.93).
The frequency of RLS among leprosy patients is significantly higher. They suffer from bad sleep quality at night which significantly affects their quality of life. So all patients affected with leprosy should be evaluated for RLS and early treatment should be started to improve their sleep.
不宁腿综合征(RLS)是一种神经系统疾病,表现为无法控制的腿部和手臂运动冲动。通常对腿部的影响大于手臂。关于麻风病中不宁腿综合征患病率的数据稀少。本研究的目的是找出麻风病患者中RLS的患病率,并确定患有RLS的麻风病患者睡眠障碍的存在情况及严重程度。
共有143名被诊断为麻风病的患者纳入本研究。使用国际不宁腿综合征研究小组描述的标准进行RLS诊断和严重程度评估。对所有被诊断为RLS的患者进行匹兹堡睡眠质量指数(PSQI)评估。
在本研究招募的143名患者中,发现56名(39.16%)患者患有RLS。匹兹堡睡眠质量指数总体平均得分较高(16.55),在出现2型麻风反应的患者(17.8)和纯神经炎型麻风患者(15.93)中该值尤其高。
麻风病患者中RLS的发生率显著更高。他们夜间睡眠质量差,这严重影响了他们的生活质量。因此,所有麻风病患者都应接受RLS评估,并应尽早开始治疗以改善睡眠。