Civelek Gul Mete, Ciftkaya Pinar Oztop, Karatas Metin
Dıskapı Yıldırım Beyazıt Education and Research Hospital, Physical Medicine and Rehabilitation Clinic, Ankara, Turkey.
Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Baskent University, Istanbul, Turkey.
J Back Musculoskelet Rehabil. 2014;27(4):537-44. doi: 10.3233/BMR-140478.
The aim of this study is to find prevalence and severity of restless legs syndrome (RLS) in patients with fibromyalgia syndrome (FMS) and detect effect of FMS and RLS coexistance on quality of sleep and life.
In this study, presence and severity of RLS were detected in patients with FMS and Pitsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS) and Fibromyalgia Impact Questionnaire (FIQ) scores of all patients were measured.
One hundred and fifteen female patients with median age 49 (39.0-57.0)[median (25-75{%} interquartile range)] were included in the study. In 42.6% of patients RLS coexisting with FMS was found. RLS was classified as moderate in 42.9% of patients and as severe in 49.0% of patients. In patients with FMS ans RLS sleep quality, daytime sleepiness and quality of life were more severely impaired (PSQI scores were 9.0 ± 4.4 vs 7.8 ± 4.3, p=0.003; ESS scores were 5.0(3.0-7.5) vs 3.0(1.0-4.3), p=0.036 and FIQ scores were 68.1 ± 9.8 vs 59.4 ± 16.9, p=0.027) compared to patients with only FMS. Prevalence of RLS was found higher in FMS than normal population and quality of sleep and quality of life were worse in patients with RLS.
Presence of RLS should be investigated in every patient with FMS and treatment plans should also cover RLS in case of coexistance with FMS. Prospective cohort studies are needed for better explanation of FMS and RLS coexistance.
本研究旨在探寻纤维肌痛综合征（FMS）患者中不安腿综合征（RLS）的患病率及严重程度，并检测FMS与RLS共存对睡眠质量和生活质量的影响。
在本研究中，检测FMS患者中RLS的存在情况及严重程度，并测量所有患者的匹兹堡睡眠质量指数（PSQI）、爱泼华嗜睡量表（ESS）和纤维肌痛影响问卷（FIQ）得分。
115名年龄中位数为49岁（39.0 - 57.0）[中位数（25 - 75%四分位数间距）]的女性患者纳入本研究。发现42.6%的患者RLS与FMS共存。42.9%的患者RLS被分类为中度，49.0%的患者为重度。与仅患有FMS的患者相比，患有FMS和RLS的患者睡眠质量、日间嗜睡及生活质量受损更严重（PSQI得分分别为9.0 ± 4.4与7.8 ± 4.3，p = 0.003；ESS得分分别为5.0(3.0 - 7.5)与3.0(1.0 - 4.3)，p = 0.036；FIQ得分分别为68.1 ± 9.8与59.4 ± 16.9，p = 0.027）。发现FMS患者中RLS的患病率高于正常人群，且RLS患者的睡眠质量和生活质量更差。
每位FMS患者均应调查RLS的存在情况，若与FMS共存，治疗方案也应涵盖RLS。需要进行前瞻性队列研究以更好地解释FMS与RLS的共存情况。
