Department of Obstetrics and Gynaecology, Faculty of Medicine, Düzce University, Düzce, Turkey.
Department of Obstetrics and Gynaecology, Faculty of Medicine, Düzce University, Düzce, Turkey.
Taiwan J Obstet Gynecol. 2014 Dec;53(4):518-22. doi: 10.1016/j.tjog.2014.08.003.
The aim of our study was to evaluate the individual contribution of parity when incorporated as another parameter into the four risk of malignancy indices (RMI 1-4) to differentiate noninvasive benign lesions from invasive malignant ovarian lesions.
After calculating RMI 1-4 for each patient included in this study, the resulting RMI scores were further multiplied by the parity score (P) of each patient to calculate the RMI parity (RMIP) score.
A cutoff value of 300 for RMIP 1 yielded 95.0% specificity, 97.4% negative predictive value (NPV), 88.5% sensitivity, and 79.3% positive predictive value (PPV) and performed better than RMI 1 in the preoperative diagnosis of invasive malignant lesions. RMIP 2 with a cutoff value of 400 yielded 95.0% specificity, 97.4% NPV, 88.5% sensitivity, and 79.3% PPV, and it also performed better than RMI 2. A cutoff value of 400 for RMIP 3 provided 97.5% specificity, 97.5% NPV, 88.5% sensitivity, and 88.5% PPV and performed better than RMI 3. However, a cutoff value of 400 for RMIP 4 provided 90.0% specificity, 97.3% NPV, 88.5% sensitivity, and 65.7% PPV but did not perform better than RMI 4 in the preoperative diagnosis of invasive malignant lesions.
RMIP 1-3 scales were more reliable tools for the preoperative diagnosis of invasive adnexal masses compared with the traditional RMI 1-3 scales.
我们研究的目的是评估在纳入四个恶性肿瘤风险指数（RMI 1-4）的另一个参数时，产次对区分非浸润性良性病变与浸润性恶性卵巢病变的个体贡献。
在计算本研究中每位患者的 RMI 1-4 后，进一步将每位患者的产次评分（P）乘以 RMI 评分，计算 RMI 产次（RMIP）评分。
RMIP 1 的截断值为 300 时，特异性为 95.0%，阴性预测值（NPV）为 97.4%，敏感性为 88.5%，阳性预测值（PPV）为 79.3%，在术前诊断浸润性恶性病变方面优于 RMI 1。截断值为 400 时的 RMIP 2 特异性为 95.0%，NPV 为 97.4%，敏感性为 88.5%，PPV 为 79.3%，也优于 RMI 2。RMIP 3 的截断值为 400 时，特异性为 97.5%，NPV 为 97.5%，敏感性为 88.5%，PPV 为 88.5%，在术前诊断浸润性恶性病变方面优于 RMI 3。然而，RMIP 4 的截断值为 400 时，特异性为 90.0%，NPV 为 97.3%，敏感性为 88.5%，PPV 为 65.7%，但在术前诊断浸润性恶性病变方面并不优于 RMI 4。
与传统的 RMI 1-3 相比，RMIP 1-3 评分更可靠地用于术前诊断附件浸润性肿块。
