Amukele Timothy K, Schroeder Lee F, Jackson J Brooks, Elbireer Ali
From Makerere University-Johns Hopkins University Clinical Core Laboratory at Infectious Diseases Institute, Kampala, Uganda; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD; and
Stanford University School of Medicine, Stanford, CA.
Am J Clin Pathol. 2015 Jan;143(1):50-6. doi: 10.1309/AJCPCYA54DWZQPQT.
To describe key characteristics (laboratory quality, test volumes, and complexity) of clinical laboratories in Kampala, Uganda (population ~1.7 million).
Cross-sectional survey using a standard questionnaire to document laboratory type and quality, as well as test menus and volumes. Quality was based on the World Health Organization-Africa Region checklist.
Of the 954 laboratories identified (a density of one laboratory per 1,781 persons), 779 (82%) performed only simple kit tests or light microscope examinations. The 95% (907/954) of laboratories for whom volumes were obtained performed an average aggregate of 13,189 tests daily, for a test utilization rate of around 2 tests per individual per year. Laboratories could be segregated into eight groups based on quality, test volume, and complexity. However, 90% of the testing was performed by just two groups: (1) low-volume (≤100 tests daily), low-quality laboratories performing simple tests or (2) high-volume (>100 tests daily), high-quality laboratories. Each of these two groups did 45% of the daily testing volume (90% combined).
Clinical laboratory density in Kampala (1/1,781 persons) is high, approaching that in the United States (1/1,347 persons). Low-volume/low-quality and high-volume/high-quality laboratories do 90% of the daily aggregate testing. Quality improvement (QI) schemes for Africa must be appropriate to low-volume laboratories as well as to the large laboratories that have been the focus of previous QI efforts.
描述乌干达坎帕拉市(人口约170万)临床实验室的关键特征(实验室质量、检测量和复杂性)。
采用标准问卷进行横断面调查,记录实验室类型和质量以及检测项目和检测量。质量依据世界卫生组织非洲区域清单。
在识别出的954家实验室中(每1781人有1家实验室),779家(82%)仅进行简单的试剂盒检测或光学显微镜检查。在获取了检测量数据的95%(907/954)的实验室中,平均每天总共进行13189次检测,每人每年的检测利用率约为2次。根据质量、检测量和复杂性,实验室可分为八组。然而,90%的检测由仅两组实验室完成:(1)低检测量(≤100次/天)、低质量且进行简单检测的实验室,或(2)高检测量(>100次/天)、高质量的实验室。这两组实验室各自完成了每日检测量的45%(合计90%)。
坎帕拉市的临床实验室密度(1/1781人)很高,接近美国(1/1347人)。低检测量/低质量和高检测量/高质量的实验室完成了每日总检测量的90%。非洲的质量改进计划必须既适用于低检测量的实验室,也适用于以往质量改进工作所关注的大型实验室。