哮喘中的中性粒细胞——综述
Neutrophils in asthma--a review.
作者信息
Ciepiela Olga, Ostafin Magdalena, Demkow Urszula
机构信息
Department of Laboratory Diagnostics and Clinical Immunology of Developmental Age, Medical University of Warsaw, Marszałkowska 24, 00-576 Warsaw, Poland.
Department of Laboratory Diagnostics and Clinical Immunology of Developmental Age, Medical University of Warsaw, Marszałkowska 24, 00-576 Warsaw, Poland.
出版信息
Respir Physiol Neurobiol. 2015 Apr;209:13-6. doi: 10.1016/j.resp.2014.12.004. Epub 2014 Dec 12.
Asthma is a chronic inflammatory disease, with an array of cells involved in the pathogenesis of the disease. The role of neutrophils in the development of bronchial asthma is found to be complex, as they may trigger activation of immunocompetent cells and are a potent source of free oxygen radicals and enzymes participating in airway remodeling. The review highlights the role of neutrophils in bronchial asthma.
哮喘是一种慢性炎症性疾病，一系列细胞参与该疾病的发病机制。中性粒细胞在支气管哮喘发展中的作用较为复杂，因为它们可能触发免疫活性细胞的激活，并且是参与气道重塑的游离氧自由基和酶的重要来源。这篇综述强调了中性粒细胞在支气管哮喘中的作用。
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