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哮喘中的中性粒细胞——综述

Neutrophils in asthma--a review.

作者信息

Ciepiela Olga, Ostafin Magdalena, Demkow Urszula

机构信息

Department of Laboratory Diagnostics and Clinical Immunology of Developmental Age, Medical University of Warsaw, Marszałkowska 24, 00-576 Warsaw, Poland.

Department of Laboratory Diagnostics and Clinical Immunology of Developmental Age, Medical University of Warsaw, Marszałkowska 24, 00-576 Warsaw, Poland.

出版信息

Respir Physiol Neurobiol. 2015 Apr;209:13-6. doi: 10.1016/j.resp.2014.12.004. Epub 2014 Dec 12.

DOI:10.1016/j.resp.2014.12.004
PMID:25511380
Abstract

Asthma is a chronic inflammatory disease, with an array of cells involved in the pathogenesis of the disease. The role of neutrophils in the development of bronchial asthma is found to be complex, as they may trigger activation of immunocompetent cells and are a potent source of free oxygen radicals and enzymes participating in airway remodeling. The review highlights the role of neutrophils in bronchial asthma.

摘要

哮喘是一种慢性炎症性疾病,一系列细胞参与该疾病的发病机制。中性粒细胞在支气管哮喘发展中的作用较为复杂,因为它们可能触发免疫活性细胞的激活,并且是参与气道重塑的游离氧自由基和酶的重要来源。这篇综述强调了中性粒细胞在支气管哮喘中的作用。

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1
Neutrophils in asthma--a review.哮喘中的中性粒细胞——综述
Respir Physiol Neurobiol. 2015 Apr;209:13-6. doi: 10.1016/j.resp.2014.12.004. Epub 2014 Dec 12.
2
[Reasearch progress on the role of neutrophils in asthma].[中性粒细胞在哮喘中作用的研究进展]
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Do neutrophils actively participate in airway inflammation and remodeling in asthma?中性粒细胞是否积极参与哮喘中的气道炎症和重塑?
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Pathogenesis of airway inflammation in bronchial asthma.支气管哮喘气道炎症的发病机制。
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Mediators of hypersensitivity and inflammatory cells in the pathogenesis of bronchial asthma.支气管哮喘发病机制中的超敏反应介质和炎症细胞
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[Airway remodeling in asthma].[哮喘中的气道重塑]
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Neutrophils in asthma pathophysiology.哮喘病理生理学中的中性粒细胞。
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