Akinkugbe F M, Akinwolere O A, Oyewole A I
Institute of Child Health, College of Medicine, University of Ibadan, Nigeria.
Afr J Med Med Sci. 1989 Sep;18(3):169-75.
Serum immunoglobulin (Ig) G, M and A were determined at 3-monthly intervals during the first year of life in 35 healthy Nigerian infants. The neonatal IgG values were high, but dropped rapidly by 3 months to about 37% of the neonatal value, and thereafter rose steadily. The neonatal IgM values dropped slightly (10%) by 3 months and then rose steadily to reach a level above the neonatal value after 1 year. IgA was not detected in most of the children during the neonatal period, but where it was detected and was measurable, the values were very low and then rose steadily until the age of 1 year. There was a suggestion that the pattern of immunoglobulin in infancy might be influenced by the level of maternal education.
在35名健康的尼日利亚婴儿出生后的第一年，每隔3个月测定一次血清免疫球蛋白（Ig）G、M和A。新生儿的IgG值较高，但在3个月时迅速下降至新生儿值的约37%，此后稳步上升。新生儿的IgM值在3个月时略有下降（10%），然后稳步上升，1年后达到高于新生儿值的水平。大多数儿童在新生儿期未检测到IgA，但在检测到且可测量的情况下，其值非常低，然后稳步上升直至1岁。有迹象表明，婴儿期免疫球蛋白的模式可能受母亲教育水平的影响。
