Iwasaki Makoto, Okajima Kazuto, Takano Tetsuzo, Misaki Hiroshi
The Department of Urology, Yamato Municipal Hospital.
Hinyokika Kiyo. 2014 Nov;60(11):575-8.
Portal venous gas is a rare complication. We present a case of hepatic portal venous gas (HPVG) and pneumatosis cystoides intestinalis (PCI) in a patient treated with docetaxel for prostate cancer. An 80-year-old man with castration-resistant prostate cancer received 5 cycles of docetaxel. Diarrhea and vomiting appeared on the 4th day of the 5th cycle. An abdominal computed tomography (CT) scan revealed HPVG and PCI. Since there were neither peritoneal irritation signs nor intestinal necrosis, we performed conservative management. The HPVG and PCI were no longer detected in the abdominal CT scan on the 18th day. Mucosal injury of the bowel wall by docetaxel might have caused HPVG and PCI. This case report is the first description of HPVG and PCI in a patient with castration-resistant prostate cancer in Japan.
门静脉气体是一种罕见的并发症。我们报告一例在接受多西他赛治疗前列腺癌的患者中出现肝门静脉气体(HPVG)和气性囊肿性肠炎(PCI)的病例。一名80岁去势抵抗性前列腺癌男性接受了5个周期的多西他赛治疗。在第5周期的第4天出现腹泻和呕吐。腹部计算机断层扫描(CT)显示有HPVG和PCI。由于既没有腹膜刺激征也没有肠坏死,我们进行了保守治疗。在第18天的腹部CT扫描中未再检测到HPVG和PCI。多西他赛对肠壁的黏膜损伤可能导致了HPVG和PCI。本病例报告是日本首例关于去势抵抗性前列腺癌患者出现HPVG和PCI的描述。