Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran; Digestive Oncology Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Digestive Oncology Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Ann Glob Health. 2014 Sep-Oct;80(5):346-57. doi: 10.1016/j.aogh.2014.09.012.
Western Asia comprises a large proportion of the world population with different ethnicities and religions inhabiting areas of diverse geographic features. The countries of this region have experienced rapid economic growth over the latter half of the 20th century, which continues to this day, resulting in major changes in lifestyle of the population.
The aim of this study was to compare the incidence and mortality of cancer in West Asia using the estimates reported by the International Agency for Research on Cancer (IARC) in Globocan-2012.
Countries with high-quality data or national data (based on the definition of the Globocan-2012) were included in the analysis. These included Bahrain, Iran, Jordan, Kuwait, Lebanon, Oman, Qatar, Saudi Arabia, and Turkey. We also found high-quality cancer data from regional cancer registries in 3 Iranian and 3 Turkish provinces. Data on cancer incidence and mortality were collected and described in tables and graphs. Spearman's correlation test was used to assess the correlation between geographic coordinates and the incidence age-standardized rate (ASR; per 100,000 person-years) of cancers.
Nine countries and 6 regional registries were included. Cancers of the lung (ASR, 33.3), prostate (24.9), bladder (19.1), stomach (16.5), and colorectal (15.9) were the most common malignancies in men. The most common cancers in women were those of the breast (35.4), colorectal (12.1), thyroid (10.3), stomach (9.2), and lung (6.7). The incidence rates of upper gastrointestinal and lung cancers were considerably higher in the northern part of this region, including Turkey and northern Iran compared with southern countries. High incidences of breast, colorectal, prostate, and bladder cancers were found in countries located in the northwest including Jordan, Lebanon, and Turkey.
The most common cancers differed by country. Consequently, cancer control programs must be tailored to the most common types of cancers in each country. Lack of high-quality data for some West Asian countries was the major limitation of this study. Therefore, as the first step of cancer control programs, it is recommended that well-structured population-based cancer registries be established in all of these countries.
西亚地区拥有世界上很大一部分人口，不同种族和宗教的人居住在地理特征多样的地区。该地区的国家在 20 世纪后半叶经历了快速的经济增长，这种增长一直持续到今天，导致人口的生活方式发生了重大变化。
本研究旨在使用国际癌症研究机构（IARC）在 Globocan-2012 中报告的数据，比较西亚癌症的发病率和死亡率。
分析中包括了数据质量高或有国家数据（根据 Globocan-2012 的定义）的国家。这些国家包括巴林、伊朗、约旦、科威特、黎巴嫩、阿曼、卡塔尔、沙特阿拉伯和土耳其。我们还从 3 个伊朗和 3 个土耳其省份的区域癌症登记处找到了高质量的癌症数据。收集和描述了癌症发病率和死亡率的数据，并以表格和图表的形式呈现。使用 Spearman 相关检验评估地理坐标与癌症发病率年龄标准化率（每 10 万人年的发病率）之间的相关性。
纳入了 9 个国家和 6 个区域登记处。男性中最常见的恶性肿瘤是肺癌（ASR，33.3）、前列腺癌（24.9）、膀胱癌（19.1）、胃癌（16.5）和结直肠癌（15.9）。女性中最常见的癌症是乳腺癌（35.4）、结直肠癌（12.1）、甲状腺癌（10.3）、胃癌（9.2）和肺癌（6.7）。与南部国家相比，该地区北部包括土耳其和伊朗北部的上消化道癌和肺癌发病率明显较高。乳腺癌、结直肠癌、前列腺癌和膀胱癌在位于西北部的国家（包括约旦、黎巴嫩和土耳其）的发病率较高。
不同国家最常见的癌症类型不同。因此，癌症控制计划必须针对每个国家最常见的癌症类型进行调整。本研究的主要局限性是一些西亚国家缺乏高质量的数据。因此，作为癌症控制计划的第一步，建议在所有这些国家建立结构良好的基于人群的癌症登记处。
