Houya I, Kimura I, Nagata M, Kuramitsu K, Kiuchi H, Sakamoto Y, Yamamoto K, Dohi Y, Kaneko K
Second Dept. of Internal Medicine, Saitama Medical College.
Gan To Kagaku Ryoho. 1989 Aug;16(8 Pt 2):2697-700.
Five patients of advanced non-small cell lung cancer with atelectasis and/or poor performance status were treated with combination MVP therapy consisting of bronchial arterial infusion (BAI) using cisplatin (50 mg) and simultaneous systemic MVP therapy. The tumor size reduced more than 50% in three patients, and less than 25% in one patient. In another patient the tumor size was not measurable. Four of five patients showed disappearance of atelectasis, and three of four patients showed improvement of performance status. Average time taken was 13 and 17 days, respectively. We expect that combination MVP therapy has beneficial effects not only for relieving local symptoms and improving performance status within shorter period, but also achieving a better prognosis.
5例晚期非小细胞肺癌伴肺不张和/或身体状况较差的患者接受了联合MVP治疗，包括使用顺铂（50mg）进行支气管动脉灌注（BAI）以及同步全身MVP治疗。3例患者肿瘤大小缩小超过50%，1例患者缩小不到25%。另一例患者肿瘤大小无法测量。5例患者中有4例肺不张消失，4例患者中有3例身体状况得到改善。平均所需时间分别为13天和17天。我们期望联合MVP治疗不仅能在较短时间内缓解局部症状和改善身体状况，还能获得更好的预后。
