Ebara M, Kita K, Yoshikawa M, Ohto M
First Dept. of Medicine, School of Medicine, Chiba University.
Gan To Kagaku Ryoho. 1989 Sep;16(9):3311-8.
Percutaneous ethanol injection (PEI) was carried out for 109 lesions in 85 patients with hepatocellular carcinoma (HCC) smaller than 3 cm in diameter during the period from Dec. 1982 to Mar. 1989. Therapeutic effect of PEI on HCC was evaluated by ultrasound showing that 15 of 68 HCCs disappeared and the remaining 53 HCCs decreased in size with regression rates ranging from 8% to 88% at 6 months after PEI. Survival rates from PEI calculated by the Kaplan-Meier method showed a 1-yr survival of 92%, a 2-yr survival of 81%, a 3-yr survival of 61%, a 4-yr survival of 55%, and a 5-yr survival of 41%. These survival rates were better than those of patients with HCCs smaller than 3 cm in size who had not received anti-cancer treatment (p less than 0.05).
1982年12月至1989年3月期间,对85例直径小于3厘米的肝细胞癌(HCC)患者的109个病灶进行了经皮乙醇注射(PEI)。通过超声评估PEI对HCC的治疗效果,结果显示68个HCC中有15个消失,其余53个HCC体积缩小,PEI后6个月的消退率为8%至88%。采用Kaplan-Meier法计算的PEI生存率显示,1年生存率为92%,2年生存率为81%,3年生存率为61%,4年生存率为55%,5年生存率为41%。这些生存率优于未接受抗癌治疗的直径小于3厘米的HCC患者(p<0.05)。