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感染单核细胞增生李斯特菌的胸主动脉瘤破裂:一例病例报告及文献综述

Ruptured thoracic aortic aneurysm infected with listeria monocytogenes: a case report and a review of literature.

作者信息

Masuda Shigeki, Takeuchi Nobuhiro, Takada Masanori, Fujita Koichi, Nishibori Yoshiharu, Maruyama Takao

机构信息

Department of Cardiology, Kawasaki Hospital, Kobe, Japan.

出版信息

Open J Cardiovasc Surg. 2013 Apr 29;6:1-7. doi: 10.4137/OJCS.S11446. eCollection 2013.

Abstract

A 75-year-old male with a history of alcoholic liver cirrhosis, sigmoid colon cancer, and metastatic liver cancer was admitted to our institution with a complaint of a prickly feeling in his chest. On admission, a chest radiograph revealed a normal cardio-thoracic ratio of 47%. Echocardiography revealed pericardial effusion and blood chemical analyses revealed elevated C-reactive protein levels (14.7 mg/dL). On day 3, chest radiography revealed cardiomegaly with a cardio-thoracic ratio of 58% and protrusion of the left first arch. Contrast-enhanced chest computed tomography revealed a saccular aneurysm in the aortic arch with surrounding hematoma; thus, a ruptured thoracic aortic aneurysm was suspected. Emergency surgery was performed, which revealed a ruptured aortic aneurysm with extensive local inflammation. The diagnosis of an infected aortic rupture was therefore confirmed. The aneurysm and abscess were resected, followed by prosthetic graft replacement and omental packing. Histopathology of the resected aneurysm revealed gram-positive bacilli; and Listeria monocytogenes was confirmed as the causative organism by culture. Postoperative course was uneventful; on postoperative day 60, the patient was ambulatory and was discharged. Here we report the case of a male with a ruptured thoracic aortic aneurysm infected with L. monocytogenes.

摘要

一名75岁男性,有酒精性肝硬化、乙状结肠癌和转移性肝癌病史,因胸部有刺痛感入住我院。入院时,胸部X线片显示心胸比率正常,为47%。超声心动图显示心包积液,血液化学分析显示C反应蛋白水平升高(14.7mg/dL)。第3天,胸部X线片显示心脏增大,心胸比率为58%,左第一弓突出。胸部增强计算机断层扫描显示主动脉弓有一个囊状动脉瘤,周围有血肿;因此,怀疑是胸主动脉瘤破裂。进行了急诊手术,结果显示主动脉瘤破裂并伴有广泛的局部炎症。因此,确诊为感染性主动脉破裂。切除动脉瘤和脓肿,随后进行人工血管置换和网膜填塞。切除的动脉瘤组织病理学检查显示革兰氏阳性杆菌;通过培养确诊为单核细胞增生李斯特菌为病原体。术后过程顺利;术后第60天,患者可下床活动并出院。在此,我们报告一例感染单核细胞增生李斯特菌的胸主动脉瘤破裂男性病例。

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